TYPE2 DIABETES

This study looked at whether a type of talk therapy (cognitive-behavioral therapy) could improve how the body uses insulin in teenage girls at risk for type 2 diabetes. The 147 participants were girls aged 12-17 with overweight or obesity, mild to moderate depression, and a famil…

This study tested the Omnipod 5, a wearable device that automatically delivers insulin, in 343 adults with type 2 diabetes. Participants used the system for 13 weeks to see if it improved blood sugar levels. The goal was to make diabetes management simpler and more effective.

This study tested whether adding social gaming (earning points and supporting each other) to a weight loss app helps adults with overweight or obesity and at least 3 risk factors for type 2 diabetes lose more weight over 12 months. About 240 adults used a mobile app to track food…

This study looked at whether a DASH-style diet (modified for diabetes) combined with lower salt intake can lower blood pressure in adults with type 2 diabetes and high blood pressure. 105 participants ate specially prepared meals for 5-week periods. The goal was to find a practic…

This study tested a medication called tirzepatide in children and teenagers aged 10 to 17 with type 2 diabetes. Participants were already taking metformin or insulin but still had high blood sugar. The goal was to see if tirzepatide could safely lower blood sugar levels better th…

This study looked at whether eating more slow-digestible starch (like in certain grains) can improve blood sugar control and reduce inflammation in people with type 2 diabetes. 53 adults with type 2 diabetes followed either a high or low slow-digestible starch diet for 3 months. …

This study tested a new medicine called efsubaglutide alfa in 59 adults with type 2 diabetes whose blood sugar remained high despite diet and exercise. Participants received an injection every two weeks for 12 weeks. The goal was to see if the drug could safely lower blood sugar …

This study tested whether a special light treatment could improve thinking, sleep, and metabolism in 25 people with mild cognitive impairment or mild Alzheimer's disease who also had sleep problems. Participants lived at home and were not blind or on insulin for diabetes. The res…

This completed Phase 4 trial looked at how evolocumab (Repatha), a cholesterol-lowering drug, affects markers of inflammation and blood clotting in 41 people with type 2 diabetes and heart disease. Participants received either evolocumab or a placebo injection every 4 weeks for 1…

This study looked at how low blood sugar (hypoglycemia) affects the body's ability to control heart rate in people with well-controlled type 2 diabetes. Researchers measured changes in baroreflex sensitivity—a key heart rate regulation mechanism—before and after inducing low bloo…

This small pilot study tested whether taking metformin 30 or 60 minutes before a meal changes how the body absorbs carbohydrates. One person with obesity and high blood sugar completed three sugar-drink tests, with metformin given at different times or not at all. The goal was to…

This study looked at 210 women who had gestational diabetes during pregnancy, comparing them to similar women without it about 8 years later. Researchers measured blood sugar, insulin, weight, and lifestyle factors to understand who develops type 2 diabetes. The goal was to find …