TYPE1DIABETES

This phase 2 trial is testing whether a probiotic called Lactiplantibacillus plantarum (Lp299v) can reduce inflammation and help preserve the body's ability to make insulin in people newly diagnosed with type 1 diabetes. The study involves 60 participants aged 3 to 45 who were di…

This study tests a single infusion of stem cells from donated umbilical cord tissue (Wharton's jelly) in 66 children and teens aged 7–21 who were diagnosed with type 1 diabetes within the last 6 months. The goal is to see if the treatment is safe and can help the body produce mor…

This study tests whether taking a probiotic supplement can reduce inflammation in children and teens (ages 5-17) recently diagnosed with type 1 diabetes. The goal is to see if changing gut bacteria can slow the disease's progression. Participants receive either a probiotic or a p…

This study tests whether cyclophosphamide, a drug that calms the immune system, can reduce insulin needs in people with a rare condition that causes fat loss (lipodystrophy) and type 1 diabetes. Ten participants will receive the treatment, and researchers will measure how much in…

This study looks at whether giving pasteurized donor milk instead of formula to newborns at risk for low breastfeeding helps them breastfeed longer and more exclusively. About 112 infants born to diabetic mothers, small for gestational age, or late preterm are randomly assigned t…

This study looks at whether giving children with a genetic risk for celiac disease a low-gluten diet (less than 3 grams per day) during their first three years of life can lower their chance of developing the disease by age 7. About 1,100 children from Sweden are taking part. The…