TREATMENT-RESISTANT SCHIZOPHRENIA
Clinical trials for TREATMENT-RESISTANT SCHIZOPHRENIA explained in plain language.
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Shock therapy maintenance may keep schizophrenia at bay
Disease control Recruiting nowThis study looks at whether maintenance electroconvulsive therapy (ECT) can help people with schizophrenia that doesn't get better with the strongest medication, clozapine. About 140 adults who improved after a course of ECT will either continue with regular ECT sessions or recei…
Matched conditions: TREATMENT-RESISTANT SCHIZOPHRENIA
Phase: NA • Sponsor: Central Institute of Mental Health, Mannheim • Aim: Disease control
Last updated May 26, 2026 08:51 UTC
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Magnetic seizures could replace ECT for schizophrenia
Disease control Recruiting nowThis study tests whether magnetic seizure therapy (MST) can safely reduce symptoms in people with schizophrenia that hasn't improved with standard medications. About 80 adults with treatment-resistant schizophrenia or schizoaffective disorder will receive MST, which uses magnetic…
Matched conditions: TREATMENT-RESISTANT SCHIZOPHRENIA
Phase: NA • Sponsor: Centre for Addiction and Mental Health • Aim: Disease control
Last updated May 26, 2026 08:29 UTC
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New hope for Tough-to-Treat schizophrenia: evenamide trial launches
Symptom relief Recruiting nowThis study tests whether a new drug called evenamide can help people with treatment-resistant schizophrenia whose symptoms are not well controlled by their current antipsychotic medications. About 400 adults will receive either evenamide or a placebo added to their usual treatmen…
Matched conditions: TREATMENT-RESISTANT SCHIZOPHRENIA
Phase: PHASE3 • Sponsor: Newron Pharmaceuticals SPA • Aim: Symptom relief
Last updated May 26, 2026 08:50 UTC
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Sleep therapy shows promise for tough schizophrenia cases
Symptom relief Recruiting nowThis study tests whether a type of talk therapy focused on sleep (CBT-I) can improve sleep, reduce psychotic symptoms, and enhance quality of life in people with treatment-resistant schizophrenia. About 60 participants will receive either CBT-I or standard therapy for 8-10 sessio…
Matched conditions: TREATMENT-RESISTANT SCHIZOPHRENIA
Phase: NA • Sponsor: Jimmi Nielsen • Aim: Symptom relief
Last updated May 26, 2026 08:34 UTC
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Brain training zaps hallucinations in Drug-Resistant schizophrenia
Symptom relief Recruiting nowThis study tests a non-invasive brain training technique called real-time fMRI neurofeedback to help people with schizophrenia who still hear voices despite medication. Participants learn to control brain activity linked to auditory hallucinations. The goal is to reduce the inten…
Matched conditions: TREATMENT-RESISTANT SCHIZOPHRENIA
Phase: NA • Sponsor: Boston VA Research Institute, Inc. • Aim: Symptom relief
Last updated May 26, 2026 08:33 UTC