Magnetic seizures: a new hope for schizophrenia without the memory fog?
NCT ID NCT06672588
First seen Nov 17, 2025 · Last updated Jun 22, 2026 · Updated 33 times
Summary
This study compares Magnetic Seizure Therapy (MST) to standard Electroconvulsive Therapy (ECT) in 80 people with treatment-resistant schizophrenia or schizoaffective disorder. MST uses magnetic pulses to trigger a controlled seizure, aiming to ease symptoms like hallucinations and depression while causing fewer memory problems than ECT. Researchers will track symptom changes, thinking skills, and side effects over the treatment course.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Contact
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Locations
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Centre for Addiction and Mental Health
RECRUITINGToronto, Ontario, M6J 1H4, Canada
Contact
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University of British Columbia Hospital
RECRUITINGVancouver, British Columbia, V6T 2A1, Canada
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Magnetic Seizure Therapy (MST) device
What this could lead to
If MST works, it could offer a safer, more tolerable alternative to ECT for people with hard-to-treat schizophrenia, reducing symptoms and cognitive side effects.
What could go wrong
This is an early-stage trial with only 80 participants, so results may not apply to everyone. MST may not be as effective as ECT, and risks like seizures or memory issues remain possible.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.