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New combo therapy aims to ease tough schizophrenia symptoms

NCT ID NCT06574360

First seen Mar 24, 2026 · Last updated Jun 12, 2026 · Updated 13 times

Summary

This study tests whether adding a second drug that boosts NMDA receptors to a sigma-1 receptor agonist can better reduce schizophrenia symptoms than the sigma-1 drug alone. About 90 adults with schizophrenia who did not improve on at least two antipsychotics will take the combination for 8 weeks. The main goal is to see if their overall symptoms, measured by a standard scale, get better.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Department of Psychiatry, China Medical University Hospital

    RECRUITING

    Taichung, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.