TREATMENT RESISTANT DEPRESSION (TRD)

This study is testing two faster forms of non-invasive brain stimulation for people with depression that hasn't improved with standard treatments. Researchers will compare a more precise, image-guided method against a standard method and a placebo treatment. The goal is to see if…

This study is testing whether a few doses of ketamine, given alongside guided therapy sessions, can help people with treatment-resistant depression. Researchers want to see if this combination changes brain activity in ways that reduce depression symptoms and improve emotional fl…

This study aims to see if a low-carb ketogenic diet can make a type of non-invasive brain stimulation more effective for adults with depression that hasn't responded to standard medications. Participants will follow either the ketogenic diet or a standard healthy diet for several…

This study is testing a new approach for people with depression that hasn't improved with standard treatments. Researchers want to see if psilocybin, a compound from 'magic mushrooms,' can relieve depression even when its psychedelic effects are blocked by another drug called tra…

This study is testing whether a new, more precise method for targeting brain stimulation works better than the standard method for people with depression that hasn't improved with medication. Researchers will use MRI scans to create a personalized brain map for each participant t…

This early-stage study aims to find a specific brain signal pattern (an EEG biomarker) that shows how ketamine affects people with treatment-resistant depression. Researchers will give small groups of 20 participants different doses of ketamine and measure changes in their depres…