TOBACCO SMOKING
Clinical trials for TOBACCO SMOKING explained in plain language.
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Cash rewards help homeless smokers kick the habit
Disease control CompletedThis study tested whether offering financial rewards helps homeless smokers quit. 184 adults who were currently or formerly homeless received smoking coaching, a prescription for a quit-smoking drug, and some also got cash rewards for staying smoke-free. Researchers checked if th…
Matched conditions: TOBACCO SMOKING
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated May 26, 2026 04:17 UTC
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FDNY firefighters get enhanced help to kick the habit and cut lung cancer risk
Disease control CompletedThis study tested a more intensive program to help retired FDNY firefighters quit smoking. 23 participants were randomly assigned to either standard care or an enhanced program that included automatic enrollment, personalized counseling based on lung tests, and medication startin…
Matched conditions: TOBACCO SMOKING
Phase: PHASE4 • Sponsor: Albert Einstein College of Medicine • Aim: Disease control
Last updated May 18, 2026 12:14 UTC
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Can a virtual counselor help you kick the habit?
Disease control CompletedThis study tested a new computer program called C-Raven that uses a virtual counselor to help people quit smoking. The program was tested with 18 adults in two clinics at Johns Hopkins Hospital. Researchers wanted to see if people would use the program and if it helped them stop …
Matched conditions: TOBACCO SMOKING
Phase: NA • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated May 18, 2026 12:11 UTC
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Longer Pre-Quit drug course may boost smoking cessation success
Disease control CompletedThis study tested whether taking varenicline (a prescription drug that reduces cravings) for 4 weeks before quitting smoking works better than the standard 1-week pre-quit course. 320 smokers were randomly assigned to either the extended or standard schedule, and all received cou…
Matched conditions: TOBACCO SMOKING
Phase: PHASE3 • Sponsor: State University of New York at Buffalo • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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Guam school program aims to stop youth vaping and betel nut use before it starts
Prevention CompletedThis study tested a new school-based curriculum designed to prevent e-cigarette, tobacco, and betel (areca) nut use among middle school students in Guam. Over 500 students aged 11-15 participated in a randomized trial comparing the new program to standard education. The goal was …
Matched conditions: TOBACCO SMOKING
Phase: NA • Sponsor: University of Guam • Aim: Prevention
Last updated May 26, 2026 04:26 UTC
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Free samples of Stop-Smoking drugs tested in remote trial
Symptom relief CompletedThis study tested whether mailing free samples of varenicline or nicotine patches/lozenges helps smokers quit. 652 daily smokers were randomly assigned to receive a free sample of varenicline, nicotine products, or no sample. Participants completed surveys and daily diaries for 6…
Matched conditions: TOBACCO SMOKING
Phase: PHASE1, PHASE2 • Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated May 26, 2026 04:22 UTC
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Zapping the brain to kick the habit: new hope for smokers with HIV?
Symptom relief CompletedThis small study tested whether a type of brain stimulation called TMS could reduce smoking cravings and attention to smoking cues in people living with HIV/AIDS. Four participants received either real or fake TMS sessions. The goal was to see if TMS could help them focus less on…
Matched conditions: TOBACCO SMOKING
Phase: NA • Sponsor: Gopalkumar Rakesh • Aim: Symptom relief
Last updated May 26, 2026 03:57 UTC
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New program aims to help hospitalized HIV patients kick the habit
Symptom relief CompletedThis study tested a two-session computer program plus a community health worker to help hospitalized people with HIV quit smoking. 22 participants joined to see if the approach was practical and liked by patients. The goal was to boost readiness to quit and use of nicotine replac…
Matched conditions: TOBACCO SMOKING
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated May 22, 2026 13:51 UTC
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Heated tobacco vs. cigarettes: which pollutes the air more?
Knowledge-focused CompletedThis study measured the chemicals released into the air by heated tobacco products and regular cigarettes in a sealed room. 32 adult smokers used either product as they normally would, while sensors tracked pollutants like carbon monoxide, nicotine, and formaldehyde. The goal was…
Matched conditions: TOBACCO SMOKING
Sponsor: Altria Client Services LLC • Aim: Knowledge-focused
Last updated May 26, 2026 04:11 UTC
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Sedatives tested to see if they curb smoking urges
Knowledge-focused CompletedThis study looked at how different sedatives (ketamine, midazolam, dexmedetomidine, or a placebo) affect cigarette cravings and smoking behavior in 20 daily smokers. Participants received a single intravenous dose and reported their cravings and withdrawal symptoms. The goal was …
Matched conditions: TOBACCO SMOKING
Phase: EARLY_PHASE1 • Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC
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Can training clinic staff help more people with mental illness quit smoking?
Knowledge-focused CompletedThis study looked at whether training staff in community mental health clinics can improve how they help patients quit smoking. Researchers worked with 91 clinic staff members to see if their knowledge and confidence in providing smoking cessation support increased. The goal was …
Matched conditions: TOBACCO SMOKING
Phase: NA • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated May 22, 2026 13:51 UTC
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JUUL vs. cigarettes: which delivers nicotine faster?
Knowledge-focused CompletedThis study looked at how nicotine enters the body when people use JUUL e-cigarettes compared to smoking regular tobacco cigarettes. Seventeen healthy adults took part, and researchers measured nicotine levels and heart rate after each product. The goal was to understand the diffe…
Matched conditions: TOBACCO SMOKING
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 04, 2026 16:23 UTC