THROMBOSIS

This study tests a special stopper (needle-free connector) for long IV catheters that prevents blood from flowing back. The goal is to reduce problems like blockages, infections, and pain. About 62 hospitalized adults who need a long IV line for at least 7 days will take part.

This study tests if a single dose of gruticibart can prevent blood clots that often form when a catheter is placed in a vein. About 90 adults getting a catheter will receive the drug and be monitored for clots and bleeding. The goal is to reduce pain and swelling while avoiding t…

This study looks at how artificial sweeteners (saccharin, sucralose) and a natural one (erythritol) affect blood sugar control, blood clotting, and heart disease risk in 80 adults with prediabetes. Participants will be assigned to one of four groups and consume a sweetener or wat…

This study will look back at the medical records of 50 adult ICU patients with COVID-19 who needed a special life support machine (VV-ECMO). The goal is to understand how often these patients have serious bleeding or blood clots, and how blood transfusions and blood thinners affe…

This study looks at how well platelets work in people on a life-support machine called ECMO. The goal is to understand why these patients often have serious bleeding. Researchers will measure platelet function over several days in 40 adults. They hope to find links between platel…

This study looks at how safe current blood thinner management is for 700 cancer patients who need surgery or medical procedures. Researchers will track bleeding and clotting problems within 30 days after surgery. The goal is to learn how to improve care and lower these risks in t…