THROMBOCYTOPENIA

This study is testing whether an infusion of umbilical cord blood can safely help cancer patients whose platelet counts have dropped dangerously low due to their cancer treatments. Researchers will give the infusion to 25 patients aged 12-65 and closely monitor their platelet lev…

This program provides access to the drug eltrombopag for patients with medically significant low platelet counts (thrombocytopenia) who meet specific eligibility criteria. It is for patients with certain conditions like chronic immune thrombocytopenia (ITP), severe aplastic anemi…

This is an early safety study testing a single injection of specialized cells derived from umbilical cord blood. The goal is to see if the injection is safe and can help raise platelet counts in cancer patients whose platelets have dropped due to chemotherapy or other cancer trea…

This study aims to find the safest platelet transfusion level for extremely premature infants born between 23 and 27 weeks. Researchers will compare whether using a lower platelet count threshold for transfusions works as well as the current higher threshold at preventing serious…

This study is testing a targeted radiation drug called 177Lu-PSMA-617 in men with advanced prostate cancer that has spread to the bone marrow and caused low blood cell counts. The main goal is to see if the treatment is safe and effective for this specific group of patients who o…

This study is testing whether giving a whole blood transfusion helps children survive severe malaria when they also have dangerously low platelet counts. Researchers in Zambia will randomly assign 132 children to either receive the transfusion or not, then track their recovery. T…

This study is testing if a drug called luspatercept can safely improve low blood cell counts in people with Clonal Cytopenia of Undetermined Significance (CCUS). CCUS is a condition where people have persistently low blood counts and genetic changes that put them at risk for deve…

This study aims to find the safest way to treat blood clots in cancer patients who also have low platelet counts, which increases their risk of dangerous bleeding. Fifty patients will be randomly assigned to receive either a full dose of blood thinners with platelet transfusions …

This study is testing whether the breast cancer drug T-DM1 can be safely given to patients who previously developed low platelet counts (thrombocytopenia) from chemotherapy. Researchers will enroll 56 breast cancer patients whose platelet counts have recovered after experiencing …

This study is testing if a drug called etamsylate can prevent serious bleeding in patients who have low platelet counts after a stem cell transplant. About 404 adult patients will be randomly assigned to receive either etamsylate or a placebo (inactive substance) to see which is …

This study is testing whether a specific lab test that looks for antibodies against a person's own platelets can help doctors diagnose immune thrombocytopenia (ITP) faster and more accurately. It will enroll 225 adults who have been found to have low platelet counts. The goal is …