STRESS URINARY INCONTINENCE

This study was testing a new medicine called VMB-100, an mRNA injection into the urethra to help regenerate muscle and reduce urine leakage in women with moderate stress urinary incontinence. It was designed for pre- or peri-menopausal women aged 18-55 who had not improved with s…

This study looks at how well the GYNECARE TVT EXACT sling works over 5 to 10 years in women with stress urinary incontinence (leaking urine when coughing or sneezing). About 200 women who had the surgery are checked to see if they are still dry and how their symptoms and quality …

This study tests a new treatment called AMDC-USR (iltamiocel) for women who still have stress urinary incontinence after previous surgery. It uses the patient's own muscle cells injected into the urinary sphincter to strengthen it. Half of the 96 participants receive the cell tre…

This study tests whether a non-invasive magnetic stimulation device can strengthen pelvic floor muscles and reduce or stop stress urinary incontinence in women. About 158 adult women with confirmed stress incontinence will receive the treatment and report their symptoms using sta…

This study looks at whether doing pelvic floor physical therapy before prostate surgery (HoLEP) can help men regain bladder control faster after the operation. About 72 men who are already scheduled for HoLEP will be split into two groups: one starts therapy before surgery and co…

This study tests whether a 2-minute perineal massage before a pessary check can reduce pain and improve comfort for women using a pessary for prolapse or incontinence. About 68 participants will each receive both the massage and a standard gel-only application at separate visits,…

This study tests whether injecting Botox into the bladder muscle can reduce urine leakage in women with stress urinary incontinence. About 20 women who have not improved with other treatments will receive the injection and be monitored for changes in leakage and side effects. The…

This study tests whether a laser applied to the vagina can help women with stress urinary incontinence (leaking urine when coughing, sneezing, or exercising). About 144 women will receive the laser treatment and be followed for 6 months. The main goal is to see if the treatment r…

This study tests a new device called PelviSense that helps women with stress urinary incontinence (leaking urine when coughing, sneezing, or exercising) strengthen their pelvic floor muscles using biofeedback. About 132 women aged 18-60 will either use the device along with stand…

This study compares two surgical sling methods (single-incision vs. retropubic) for treating stress urinary incontinence in women undergoing minimally invasive pelvic organ prolapse repair. About 180 women will be randomly assigned to one of the two sling types. The goal is to se…

This study looks at how blood supply to the urethra relates to bladder pressure in people with and without stress urinary incontinence (leakage when coughing or sneezing). Researchers will use advanced ultrasound imaging to measure blood flow and compare it to standard pressure t…