STAGE III RECTAL CANCER AJCC V8
Clinical trials for STAGE III RECTAL CANCER AJCC V8 explained in plain language.
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Could an immunotherapy boost help fight this stubborn cancer?
Disease control OngoingThis study looks at whether adding the immunotherapy drug nivolumab to the usual two-drug treatment (encorafenib and cetuximab) works better at shrinking tumors in people with a specific type of advanced colorectal cancer that has a BRAF gene mutation. About 84 adults whose cance…
Matched conditions: STAGE III RECTAL CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 01, 2026 15:42 UTC
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New combo therapy shows promise for tough rectal cancers
Disease control OngoingThis study tests whether giving two immunotherapy drugs (nivolumab and ipilimumab) along with a short course of radiation can shrink advanced rectal cancers before surgery. It includes 31 adults with a specific genetic type of rectal cancer (MSI-H/dMMR) that has spread locally. T…
Matched conditions: STAGE III RECTAL CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 30, 2026 15:51 UTC
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New combo therapy for rectal cancer moves to safety testing
Disease control OngoingThis early-stage study tests the safety of combining the chemotherapy drug TAS-102 with radiation therapy for people with stage II or III rectal cancer that hasn't been treated yet. About 19 participants will receive the drug along with radiation before surgery to find the safest…
Matched conditions: STAGE III RECTAL CANCER AJCC V8
Phase: PHASE1 • Sponsor: OHSU Knight Cancer Institute • Aim: Disease control
Last updated Apr 30, 2026 15:50 UTC
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Blood tests could unlock secrets of rectal cancer
Knowledge-focused OngoingThis study looks at tiny pieces of cancer cells or DNA floating in the blood of people with rectal cancer. Researchers want to see if these "circulating tumor elements" can tell us how the cancer responds to standard treatment. They will also compare results from cancer patients …
Matched conditions: STAGE III RECTAL CANCER AJCC V8
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated May 01, 2026 15:39 UTC