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New hope for hard-to-treat colorectal cancer: drug duo aims to shrink tumors

NCT ID NCT04599140

First seen Jan 26, 2026 · Last updated May 23, 2026 · Updated 18 times

Summary

This study tests a combination of two drugs, SX-682 and nivolumab, in people with a specific type of advanced colorectal cancer (RAS-mutated, MSS) that has spread or can't be removed. The goal is to see if the combo can shrink tumors or slow the cancer's growth. About 51 adults will take part, and the main focus is on safety and finding the best dose.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.