STAGE IIIC RECTAL CANCER AJCC V8
Clinical trials for STAGE IIIC RECTAL CANCER AJCC V8 explained in plain language.
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New study tests if chemo alone can save rectal cancer patients from surgery
Disease control Recruiting nowThis early-phase trial is testing whether people with stage II-III rectal cancer can safely avoid surgery by using chemotherapy followed by active surveillance (close monitoring) instead of immediate surgery. The goal is to preserve the rectum and avoid the need for a permanent c…
Matched conditions: STAGE IIIC RECTAL CANCER AJCC V8
Phase: EARLY_PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 08:40 UTC
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New combo aims to save rectum from surgery in rectal cancer patients
Disease control Recruiting nowThis early-phase study tests whether a short course of radiation followed by chemotherapy can shrink advanced rectal tumors enough to avoid surgery. About 25 people with stage II or III rectal cancer will receive this treatment. The goal is to preserve the rectum and improve qual…
Matched conditions: STAGE IIIC RECTAL CANCER AJCC V8
Phase: PHASE1 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated May 26, 2026 08:19 UTC
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New scan could better reveal rectal Cancer's response to treatment
Diagnosis Recruiting nowThis early-phase study tests a special PET scan using a substance called 64Cu-M5A to see how well it shows tumor activity in people with advanced rectal cancer. About 15 participants will get the scan before and after standard chemotherapy and radiation, and the results will be c…
Matched conditions: STAGE IIIC RECTAL CANCER AJCC V8
Phase: EARLY_PHASE1 • Sponsor: City of Hope Medical Center • Aim: Diagnosis
Last updated May 26, 2026 08:31 UTC
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Researchers track daily life after rectal cancer surgery
Knowledge-focused Recruiting nowThis study follows 430 people with rectal cancer (stages I–IV) to see how surgery affects their quality of life. Participants fill out questionnaires about their health and daily activities. The goal is to learn what matters most to patients after treatment, not to test a new dru…
Matched conditions: STAGE IIIC RECTAL CANCER AJCC V8
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated May 26, 2026 08:44 UTC
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Blood test may spare rectal cancer patients from surgery
Knowledge-focused Recruiting nowThis study looks at whether a simple blood test can help doctors decide if rectal cancer patients can avoid surgery and keep their rectum. Researchers will measure tiny bits of tumor DNA in the blood (ctDNA) before, during, and after standard treatment in 50 adults with stage II …
Matched conditions: STAGE IIIC RECTAL CANCER AJCC V8
Sponsor: OHSU Knight Cancer Institute • Aim: Knowledge-focused
Last updated May 18, 2026 11:58 UTC