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New immunotherapy combo could shrink colon tumors before surgery

NCT ID NCT07595874

First seen May 24, 2026 · Last updated May 24, 2026

Summary

This study tests whether giving two immunotherapy drugs (botensilimab and balstilimab) before surgery can shrink tumors and improve outcomes for people with advanced colon or rectal cancer that can be removed. About 100 adults with stage IIB to IIIC colorectal cancer will receive these drugs before their planned surgery. The goal is to see if this approach helps more patients stay cancer-free for two years compared to standard treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CTCA at Western Regional Medical Center

    Goodyear, Arizona, 85338, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • City of Hope Atlanta Cancer Center

    Newnan, Georgia, 30265, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • City of Hope Corona

    Corona, California, 92882, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • City of Hope Medical Center

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • City of Hope Seacliff

    Huntington Beach, California, 92648, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • City of Hope South Pasadena

    South Pasadena, California, 91030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • City of Hope Upland

    Upland, California, 91786, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • City of Hope at Chicago

    Zion, Illinois, 60099, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • City of Hope at Illinois Chicago Downtown

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • City of Hope at Irvine Lennar

    Irvine, California, 92618, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • City of Hope at Long Beach Elm

    Long Beach, California, 90813, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.