STAGE II PANCREATIC CANCER AJCC V8

This early-phase trial tests a combination of two drugs, calaspargase pegol-mknl and cobimetinib, in 15 people with advanced or metastatic pancreatic cancer. The goal is to find the safest dose and see if the combo can shrink tumors by cutting off their nutrient supply. It is a s…

This study tests whether a combination of two drugs, lenvatinib and pembrolizumab, can help keep advanced pancreatic cancer from getting worse. The trial involves 28 adults whose cancer cannot be removed by surgery and who have already responded to initial treatment. The goal is …

This early-stage trial tests the safety of combining two drugs (olaparib and durvalumab) with radiation therapy for people with locally advanced pancreatic cancer that cannot be removed by surgery. The goal is to see if this triple approach can help control tumor growth. About 18…

This early-phase study tests whether adding losartan (a blood pressure medicine) to a shorter, higher-dose radiation treatment can help people with pancreatic cancer that is hard to remove surgically. The main goal is to check for side effects and find the safest dose. About 22 a…

This study tests a new method called sonoporation, which uses ultrasound and tiny gas bubbles to help chemotherapy drugs get into cancer cells more effectively. The trial includes 120 adults with advanced or hard-to-remove pancreatic cancer who are already receiving standard chem…

This early-phase study tests a new drug combination for people with advanced pancreatic cancer that has a specific marker (mesothelin). The treatment pairs a targeted chemotherapy with immunotherapy drugs and standard chemo to see if it's safe and what dose works best. About 74 a…

This early-stage trial aimed to test the safety of a new treatment called STIL101 for people with advanced pancreatic, colorectal, kidney, cervical cancer, or melanoma that has spread or cannot be removed. STIL101 is made from a patient's own immune cells taken from their tumor, …