New drug combo aims to shrink inoperable pancreatic tumors
NCT ID NCT05411094
First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 38 times
Summary
This early-stage trial tests the safety of combining two drugs (olaparib and durvalumab) with radiation therapy for people with locally advanced pancreatic cancer that cannot be removed by surgery. The goal is to see if this triple approach can help control tumor growth. About 18 participants will take part in this study, which is currently on hold.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Los Angeles General Medical Center
Los Angeles, California, 90033, United States
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
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UC Irvine Health/Chao Family Comprehensive Cancer Center
Orange, California, 92868, United States
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UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
Irvine, California, 92612, United States
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UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, 27599, United States
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USC / Norris Comprehensive Cancer Center
Los Angeles, California, 90033, United States
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University Health Network-Princess Margaret Hospital
Toronto, Ontario, M5G 2M9, Canada
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University of Michigan - Brighton Center for Specialty Care
Brighton, Michigan, 48116, United States
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University of Michigan Rogel Cancer Center
Ann Arbor, Michigan, 48109, United States
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University of Wisconsin Carbone Cancer Center - Eastpark Medical Center
Madison, Wisconsin, 53718, United States
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University of Wisconsin Carbone Cancer Center - University Hospital
Madison, Wisconsin, 53792, United States
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.