STAGE II LUNG CANCER AJCC V8

This study compares two standard approaches for people with stage II-IIIB non-small cell lung cancer that can be removed with surgery. One group gets chemotherapy and immunotherapy both before and after surgery (perioperative), while the other gets it only after surgery (adjuvant…

This study is testing whether giving a combination of two immunotherapy drugs (cemiplimab and fianlimab) before surgery can kill more cancer cells in people with early-stage non-small cell lung cancer. About 60 adults with stage IB to IIIB lung cancer will receive the drug combo …

This study tests whether giving the immunotherapy drug durvalumab after surgery can help prevent early-stage non-small cell lung cancer from returning. About 306 people who have had their lung cancer completely removed will either receive durvalumab or be closely watched without …

This study looks at whether adding the immunotherapy drug pembrolizumab to standard chemotherapy after lung cancer surgery can help people live longer without the cancer coming back. About 1,210 adults with stage II to IIIB non-small cell lung cancer that was removed by surgery w…

This study tests whether artificial intelligence (AI) can help doctors choose the right radiation dose for each person with lung cancer. About 70 participants will receive a precise type of radiation called SBRT, with the dose guided by an AI tool. The goal is to see if this pers…

This study looks at whether updating radiation treatment plans at set times during therapy can lower side effects for people with non-small cell lung cancer. As tumors shrink from radiation, healthy tissue can get exposed, so researchers want to see if planned re-designs help. Ab…

This study tests whether a special yoga program can improve physical function, fatigue, sleep, and quality of life for people with lung or esophageal cancer who are getting radiation therapy, and also for their family caregivers. About 400 patient-caregiver pairs will take part. …

This study tests whether a home-based breathing exercise program can help lung cancer survivors (stages I-III) breathe easier, feel less tired, and stay active. About 100 people who have finished surgery and other treatments will participate. The goal is to see if these exercises…

This study tests whether doing special breathing exercises for several weeks before lung cancer surgery can lower the chance of serious lung problems like pneumonia or breathing failure after the operation. About 220 adults with stage I to IIIB lung cancer will either do the brea…

This study looks at two standard ways to remove lung cancer in early-stage patients. The goal is to see if tying off the vein before the artery during surgery reduces the amount of tumor DNA released into the bloodstream. About 100 adults with stage I-III non-small cell lung canc…

This study looks at whether giving early-stage lung cancer patients information about quality of life helps them feel better about their treatment choice between surgery and radiation. About 150 adults with stage I-II lung cancer will take part. The goal is to see if this extra i…