SJOGREN'S SYNDROME

This study is testing whether an investigational drug called HZN-1116 can safely reduce disease activity and ease symptoms in people with Sjögren's syndrome, an autoimmune disease. About 209 participants will receive either the drug or a placebo as a weekly injection for 48 weeks…

This early-stage study is testing the safety and initial effects of a new cell therapy called RD06-04 for people with active, severe autoimmune diseases. The therapy involves modifying a patient's own immune cells (CAR-T cells) to target and remove certain harmful immune cells. T…

This study is testing the safety and side effects of a drug called tofacitinib in adults with Sjogren's syndrome, an autoimmune disease that causes severe dryness. For about six months, 23 participants will take either the drug or a placebo pill. Researchers will monitor for side…

This large, late-stage study is testing whether an investigational drug called dazodalibep can reduce the widespread disease activity in people with moderate-to-severe Sjögren's syndrome. It involves 651 participants who will receive either the drug or a placebo to see if it safe…

This study is testing different ways to help people with inflammatory arthritis who face life challenges like unstable housing or transportation issues that make it hard to get medical care. It compares three levels of support: a simple resource list, help from a community specia…

This study is checking if the Shingrix shingles vaccine is safe and works well for people with autoimmune rheumatic diseases like lupus or rheumatoid arthritis. These patients are at high risk for shingles but are often on medications that weaken the immune system. Researchers ar…

This study aims to understand if changes in gut bacteria and gut lining markers are linked to changes in Sjögren's syndrome disease activity. Researchers will observe 50 patients with primary Sjögren's syndrome, measuring specific blood markers and quality of life over time. The …