SAFETY

This study is checking how safe the Prevenar 20 vaccine is once it's used in Korea. About 660 people aged 6 weeks and older who are prescribed the vaccine will get one dose. Researchers will track any side effects for 28 days after vaccination.

This study tests an experimental drug called HY07121 in people with advanced solid tumors that have not responded to standard treatments. The trial has two parts: first, finding a safe dose and checking for side effects; second, seeing if the drug shrinks tumors. About 258 partic…

This phase 2 trial is testing whether adding an immunotherapy drug (AK104) to standard chemotherapy and a targeted therapy (cetuximab or bevacizumab) can shrink tumors in people with a specific type of advanced colorectal cancer (MSS type) that has already been treated once. The …

This early-stage trial is testing a new drug called GenSci098 in 76 adults with active thyroid eye disease (TED). The main goal is to check the drug's safety and how the body processes it at different doses. Participants will receive either the drug or a placebo as a shot under t…

This early-stage study tests a single injection of a new drug called GenSci098 in 24 adults with Graves' disease, a condition where the thyroid is overactive. The main goal is to check if the drug is safe and how the body handles it. Participants will be monitored for side effect…

This early-stage study tests a new treatment called XS228, made from special stem cells that can become nerve cells. The goal is to see if injecting these cells into the spine is safe and tolerable for people who had a spinal cord injury 2 to 8 weeks ago. Up to 12 adults with inj…

This early-stage study tests whether stem cells from human amniotic fluid can help heal painful skin wounds (calciphylaxis) in people with chronic kidney disease. Nine participants will receive the stem cell treatment, and researchers will measure wound healing and pain levels. T…

This study tests an experimental drug, HYP-2090PTSA, in people with advanced solid tumors that have a specific genetic change called KRAS mutation. The trial has two parts: first, finding the safest dose, and then testing how well that dose works in certain cancers. About 257 adu…

This early-stage study tests a new injection called GenSci134 in healthy adults and in patients with adult growth hormone deficiency. The main goal is to check safety and side effects. The study is currently recruiting 64 participants.

This study tests a new pain medicine called oliceridine against two standard drugs (morphine and sufentanil) for pain after lower back surgery. About 90 adults having lumbar spine surgery will receive one of the three medicines through a pump they control. The goal is to see whic…

This study tests an experimental drug called IRL757 in 75 people with Parkinson's disease who also have apathy (loss of interest or motivation). The main goal is to see if the drug is safe and tolerable over 12 weeks. Researchers will also check if it helps improve apathy symptom…

This early-stage study tests whether psilocybin (the active ingredient in magic mushrooms) combined with talk therapy can safely reduce demoralization—a deep sense of hopelessness—in people with advanced cancer. Fifteen adults aged 18-70 with stage 3 or 4 cancer and high demorali…

This pilot study is testing whether taking curcumin (the active ingredient in turmeric) for two weeks can cross into the brain and attach to amyloid beta proteins, which are linked to Alzheimer's disease. Researchers will use eye imaging to detect these proteins and also check ho…

This early-stage study tests a new antibiotic combination (ceftibuten-ledaborbactam) in 46 healthy adults aged 18-55. The goal is to check safety and how the drug moves through the body, not to treat any disease. Participants will stay at a clinic for several days and have follow…

This study is checking if taking a supplement called palmitoylethanolamide (PEA) every day for a year is safe for healthy adults. About 200 volunteers aged 18 and older will take either PEA or a placebo pill. Researchers will track side effects, vital signs, and blood tests over …

This study surveys 400 doctors, nurses, and respiratory therapists worldwide to understand how non-invasive ventilation (breathing support via mask or helmet) is used outside intensive care units. The goal is to identify current practices, patient outcomes, and barriers to safer,…

This early-stage study tests whether a single inhaled dose of RCS-21 is safe and tolerable in 24 healthy volunteers aged 18 to 64. Participants receive either the drug or a placebo and are closely monitored for side effects and how the drug moves through the body. The study does …