Rotator cuff tear

This study tests whether a patch made from donated placental tissue can help rotator cuff tears heal better after surgery. Half of the 120 participants will get the patch along with standard repair, and the other half will get standard repair alone. An MRI one year later will che…

This trial tests whether BPC-157, a synthetic peptide, can improve tendon healing and strength after rotator cuff repair surgery. About 20 adults with a full-thickness rotator cuff tear will receive either BPC-157 or a placebo injection daily for 90 days after their operation. Re…

This trial tests whether injecting tranexamic acid into the shoulder bone before rotator cuff repair improves the surgeon's view during the procedure. Sixty adults scheduled for arthroscopic rotator cuff repair will receive either the drug or a placebo. The goal is to see if this…

This early-phase trial tests whether tendon stem cells can help rotator cuff tears heal better after surgery. About 107 adults with small to medium tears will receive either standard repair or repair plus stem cells placed at the injury site. The study will check for side effects…

This study will check if a new physical exam called Said's test can accurately diagnose biceps tendon injuries in the shoulder. Researchers will test 144 adults, including those with shoulder injuries and healthy volunteers. Two doctors will perform the new test and standard test…

This study tests whether a mobile app with AI-guided exercise videos and reminders helps people recover better after arthroscopic rotator cuff repair compared to standard paper instructions. About 102 adults who need surgery will be randomly assigned to use the app or follow pape…

This study tests whether a special device called H-Wave can help people recover faster and with less pain after rotator cuff repair surgery. About 80 adults aged 18-64 will either receive standard care or standard care plus the H-Wave device. Researchers will track pain, medicati…

This study compares two surgical techniques for the biceps tendon—tenotomy (cutting the tendon) and tenodesis (reattaching it)—in 50 adults aged 50-70 undergoing rotator cuff repair. The goal is to see which method leads to less pain, better shoulder function, and stronger grip a…

This study looks at whether starting gentle shoulder exercises soon after rotator cuff repair leads to better recovery than waiting six weeks. About 86 adults who have surgery for a torn rotator cuff will be randomly assigned to either early or delayed rehabilitation. Researchers…

This study will follow 50 adults having arthroscopic rotator cuff repair to see if a condition called central sensitization—where the nervous system is overly sensitive to pain—affects their recovery. Before surgery and 3 months after, researchers will measure pain and shoulder f…