Rotator cuff tear

This phase 2 trial tests whether a patient's own fat-derived cells (stromal vascular fraction) can improve healing after surgical repair of a chronic rotator cuff tear. The study enrolls 56 adults aged 45-65 with full-thickness tears who have not improved with physical therapy. T…

This trial tests whether injections of PRP lysate, a product made from a patient's own blood platelets, can improve shoulder pain, strength, and tendon tear size in adults with partial rotator cuff tears. Participants receive either PRP lysate or hypertonic dextrose prolotherapy,…

This study tests whether injecting atelocollagen and hyaluronic acid during rotator cuff surgery improves healing. 124 people aged 40-75 with confirmed tears are enrolled. They receive one or both injections during arthroscopic repair and are followed for 2 years with MRI scans a…

This study compares two common injections—platelet-rich plasma (PRP) and corticosteroids—given during arthroscopic rotator cuff repair. 387 adults with full-thickness supraspinatus tears are randomly assigned to receive PRP, corticosteroid, or a placebo injection during surgery. …

This study tests a new injection called NEMO-103 to see if it makes shoulder MRI pictures clearer for diagnosing problems like torn tendons or cartilage. About 85 adults with known or suspected shoulder issues will get both a regular MRI and one with the injection. The goal is to…

This trial compares two pain medications, tramadol and tapentadol, to see which provides better pain relief after arthroscopic rotator cuff repair surgery. Adults aged 18-80 undergoing this elective shoulder surgery will receive one of the two drugs as part of a multimodal pain m…

This study compares physical therapy delivered through video calls to traditional in-person therapy for 50 young elite baseball players with rotator cuff problems. The goal is to see if remote therapy is as effective at improving shoulder function and reducing pain, and whether i…

This study compares two recovery programs after rotator cuff repair surgery. One group follows standard care—wearing a sling for 6 weeks with limited movement. The other group starts moving sooner, guided by comfort rather than strict restrictions. Researchers will measure should…

This study looks at how the repaired rotator cuff tendon moves after surgery, which may affect recovery. 125 people getting rotator cuff repair will have small markers placed on the tendon during surgery. CT scans and MRIs over 5 years will track tendon position and healing, and …