RETINOBLASTOMA

This early-phase study tests a new treatment for children and young adults (up to age 26) with solid tumors that have come back or not responded to standard therapy. The treatment uses the patient's own immune cells, which are modified in a lab to recognize and attack a protein c…

This early-phase study tests a personalized cell therapy for children and young adults (ages 1–30) whose solid tumors have come back or not responded to standard treatment. Researchers take a patient's own immune T cells, modify them to recognize and attack cancer cells that carr…

This study tests whether a combination of chemotherapy drugs (VP16 and carboplatin) followed by local heat therapy can control retinoblastoma, a rare eye cancer in children, without needing to remove the eye or use radiation. It involves 133 children with different stages of the …

This study looks at whether giving chemotherapy (and sometimes radiation) after removing the eye can prevent retinoblastoma from coming back outside the eye. It involves 195 children under 10 who had one eye removed for extensive retinoblastoma. The goal is to reduce relapses and…

This study aimed to see if a smartphone app called GoCheckKids could help detect leukocoria (a white glow in the pupil) in children from birth to 10 years old. Leukocoria is an early sign of retinoblastoma, a rare eye cancer. The study was withdrawn before any participants were e…

This study examines how cancer treatment and frequent general anesthesia affect thinking skills, emotions, and quality of life in children and young adults (ages 8-35) who survived or were screened for retinoblastoma, a rare eye cancer. Researchers will assess memory, attention, …

This study follows adults who had retinoblastoma (a rare eye cancer) as children, at least five years after treatment ended. Researchers want to understand their long-term health, vision, risk of new cancers, and overall quality of life. The goal is to improve care and follow-up …