RENAL INSUFFICIENCY, CHRONIC

This study looks at whether time-restricted eating (eating only during a set window each day) can reduce protein in the urine and slow kidney decline in people with moderate chronic kidney disease. About 50 adults with stage 2-3 CKD will follow this eating pattern for 12 weeks. R…

This study tests whether a 12-week supervised exercise program during dialysis can help patients over 40 with chronic kidney disease build muscle, improve sleep, and feel better overall. Half of the 58 participants will do strength and aerobic exercises during their first 90 minu…

This study tests whether an artificial intelligence (AI) program can help people on dialysis feel less anxious and better cope with stress. Sixty adults will use personalized relaxation techniques guided by AI during their dialysis sessions. Researchers will measure changes in an…

This study looks at kidney tissue from adults with diabetic kidney disease who are already scheduled for a kidney biopsy or surgery as part of their regular care. Researchers want to understand how SGLT2 inhibitors, a type of diabetes medicine, change the kidney's molecular finge…

This study looks at how the drug eloralintide is processed by the body in people with severe kidney disease or kidney failure compared to healthy people. About 28 adults will receive a single injection under the skin. The study lasts about 14 weeks and aims to understand drug lev…

This study looks at why people with chronic kidney disease (CKD) have trouble exercising and why their blood pressure spikes during activity. Researchers will test if regular bike exercise, a drug called Kuvan, or amino acid supplements can help. The goal is to understand the bod…

This study tests a single dose of hydroxynidone capsules in 56 people with mild to severe kidney problems and healthy volunteers. The goal is to see how the drug moves through the body and if it is safe. Results will help doctors decide the right dose for patients with kidney iss…

This study follows 369 liver transplant patients who have new or worsening kidney problems. Researchers perform kidney biopsies to understand the cause of kidney damage and track how kidney function changes over time. The goal is to identify risk factors that lead to kidney failu…

This study uses special MRI scans to measure how well a donated kidney works in the recipient and how the donor's remaining kidney adapts. Researchers will follow 60 people (donors and recipients) for one year after transplant. The goal is to find better ways to select kidneys fr…

This study looks at how calcium and phosphorus from food affect people with advanced chronic kidney disease (stages 4 and 5). Researchers will compare two ways of tracking what patients eat—taking photos of meals versus writing down everything—to see which works better. The goal …

This study looks at whether a home-based exercise program is safe and practical for adults aged 60 and older who are waiting for a kidney transplant. Participants will wear an activity tracker and may be assigned to online exercise classes or usual care. The goal is to see if the…