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This study looked at how the drug LY3537982 behaves in people with different levels of kidney function. Researchers gave a single dose to 32 participants with normal kidneys, moderate kidney problems, or severe kidney problems (not on dialysis). The goal was to see how kidney imp…

This study observed 228 critically ill patients in China who needed continuous kidney dialysis. Researchers wanted to see how well pre-mixed solutions worked in everyday hospital care. They tracked how long dialysis filters lasted, checked patients' blood levels, and recorded any…

This study tested a new way to measure blood pressure in 90 people with severe kidney failure. The new method uses a different timing technique to see if it works as well as the standard arm-cuff method. The goal was to find a more accurate way to measure blood pressure in patien…

This study looked at 5 adults with Fabry disease who have been on enzyme replacement therapy since childhood for about 15 years. Researchers checked their kidney function and heart health to see how well the treatment worked over time. The goal was to gather long-term follow-up d…

This early-stage study tested the safety and how the body processes KBP-5074 in 26 healthy adults and people with mild to moderate kidney impairment. Researchers measured side effects and drug levels in the blood to help design future larger studies. No treatment was given; the g…

This study looked at 120 people having hand or wrist surgery to see if kidney failure or diabetes affects how long a nerve block lasts. Researchers measured the time it took for feeling to return after the block. The goal was to understand how these metabolic conditions change th…

This study looked at 268 adults with kidney failure who were on dialysis. Researchers used portable heart monitors to track heart rhythm problems and blood sugar changes. The goal was to see how these issues relate to the risk of heart-related death or other serious heart events …

This study looked at how different levels of kidney function affect the way the experimental brain drug iclepertin is processed in the body. 36 adults with normal or impaired kidneys took a single dose of iclepertin. Researchers measured drug levels in the blood to see if kidney …

This study looked at how the drug LY3537031 enters the blood and leaves the body in people with different levels of kidney function. 31 adults, some with kidney impairment and some healthy, took a single dose. The goal was to gather safety and processing data, not to treat any co…

This study looked at how the antibiotic ceftriaxone moves through the blood and belly fluid in 20 patients with liver cirrhosis and ascites (fluid buildup). Researchers wanted to understand if kidney problems change drug levels, which could affect safety and dosing. The goal is t…

This study looked at how the drug selpercatinib is handled by the body in people with kidney problems compared to healthy people. 37 adults took a single dose of the drug, and researchers measured how much got into the blood and how quickly it was removed. The goal was to gather …

This study looked at how the drug BI 1015550 is absorbed in people with and without kidney problems. 26 adults took a single tablet, and researchers measured drug levels in their blood over two weeks. The goal was to see if kidney issues change how the drug behaves, which helps d…