REM SLEEP BEHAVIOR DISORDER

This study tests whether carvedilol, a drug used for heart conditions, can slow the progression of Parkinson's disease in people with early warning signs like REM sleep behavior disorder. Fifteen participants will take carvedilol and have brain scans every six months for three ye…

This study tests whether an oral drug called PXS-4728A can reduce brain inflammation in 40 adults aged 50-80 with isolated REM sleep behavior disorder (iRBD), a condition often leading to Parkinson's disease. Participants receive either the drug or a placebo for 12 weeks, and bra…

This study looks at whether terazosin, a drug usually used for high blood pressure, can slow the progression of Parkinson's disease. Researchers are tracking changes in heart and brain scans of 15 people who are either in early stages or at high risk for Parkinson's. The goal is …

This study uses a special brain scan called DaTscan to look at how certain brain diseases affect the brain. Researchers will scan 500 adults with conditions like Parkinson's disease, dementia, mild cognitive impairment, or REM sleep behavior disorder. The goal is to see if DaTsca…

This study looks at whether terazosin, a drug used for high blood pressure, can change heart nerve activity in people at high risk for Parkinson's disease. Researchers are studying 15 adults with REM sleep behavior disorder (a strong early sign of Parkinson's) to see if the drug …

This study enrolls 500 adults with a sleep condition called REM sleep behavior disorder (RBD), which often leads to Parkinson's disease or similar brain disorders. Researchers will track symptoms like movement, thinking, and smell to design future trials that test treatments to p…

This study looks at whether carvedilol, a drug used for heart failure, can reverse early heart changes seen in people with a sleep disorder that puts them at high risk for Parkinson's disease. Fifteen participants with REM sleep behavior disorder or reduced sense of smell will ta…