REFRACTORY MYELODYSPLASTIC SYNDROME
Clinical trials for REFRACTORY MYELODYSPLASTIC SYNDROME explained in plain language.
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New hope for kids with tough leukemia: early trial tests drug to boost chemo
Disease control OngoingThis early-stage study is testing the safety and best dose of a new drug called uproleselan when given with two standard chemotherapy drugs (fludarabine and cytarabine). It is for children and teenagers (ages 1-17) whose acute myeloid leukemia, myelodysplastic syndrome, or mixed …
Matched conditions: REFRACTORY MYELODYSPLASTIC SYNDROME
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 03, 2026 22:56 UTC
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Scientists test Immune-Boosting combo against tough blood cancers
Disease control OngoingThis early-stage study is testing the safety and best dose of a two-drug combination for patients with advanced myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML) that has returned or not responded to prior treatment. The trial combines a chemotherapy drug (decitabine…
Matched conditions: REFRACTORY MYELODYSPLASTIC SYNDROME
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 03, 2026 14:41 UTC
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New hope for tough blood cancers: testing a Triple-Drug attack
Disease control OngoingThis study is testing a new combination of three drugs—navitoclax, venetoclax, and decitabine—for patients with a high-risk type of blood and bone marrow cancer called myelodysplastic syndrome (MDS) that has come back or hasn't responded to standard treatments. The main goals are…
Matched conditions: REFRACTORY MYELODYSPLASTIC SYNDROME
Phase: PHASE1 • Sponsor: Thomas Jefferson University • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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Radioactive 'smart bomb' tested against stubborn blood cancer
Disease control TerminatedThis early-stage trial is testing whether a radioactive antibody called lintuzumab-Ac225 can help control advanced myelodysplastic syndrome (MDS) that hasn't responded to standard treatments. The treatment works by attaching to cancer cells and delivering radiation directly to th…
Matched conditions: REFRACTORY MYELODYSPLASTIC SYNDROME
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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New pill trial targets genetic flaw in tough blood cancers
Disease control OngoingThis study is testing if a pill called olaparib can help control advanced blood cancers (acute myeloid leukemia or myelodysplastic syndrome) that have come back or haven't responded to standard treatments. It is for adults whose cancer has a specific genetic change called an IDH …
Matched conditions: REFRACTORY MYELODYSPLASTIC SYNDROME
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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New hope for tough blood cancers: testing a Two-Drug attack
Disease control OngoingThis study is testing a new combination of two drugs, venetoclax and azacitidine, for patients with high-risk myelodysplastic syndrome (MDS) or chronic myelomonocytic leukemia (CMML) that has come back or stopped responding to standard treatment. The first part of the study aims …
Matched conditions: REFRACTORY MYELODYSPLASTIC SYNDROME
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 18, 2026 14:41 UTC
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New hope for tough leukemia: Triple-Drug attack enters early testing
Disease control TerminatedThis early-stage study is testing the safety and best dose of a new three-drug combination for adults with acute myeloid leukemia (AML) or related blood cancers that have come back or not responded to prior treatments. The goal is to see if adding the drug regorafenib to two exis…
Matched conditions: REFRACTORY MYELODYSPLASTIC SYNDROME
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Mar 17, 2026 13:09 UTC