RECURRENCE

This study tests whether a 24-hour active drain placed under the scalp works as well as a 24-hour passive drain placed under the brain's outer layer after surgery to remove a chronic subdural hematoma (a slow brain bleed). About 354 adults with this condition will take part acros…

This study tests whether lying flat after surgery for chronic subdural hematoma (a brain bleed) can prevent it from returning. About 830 adults aged 60 and older will be randomly assigned to either lie flat or follow standard care. The goal is to see if this simple body position …

This study follows 200 people who receive the Triathlon Hinge Knee system, either as a first knee replacement or to fix a previous one. Researchers will check how well the knee works and how long it lasts over 1, 2, 6, and 10 years. The goal is to see if the implant stays in plac…

This study looks at using a blood test that detects tiny bits of tumor DNA (ctDNA) to guide chemotherapy decisions in people with stage II colon cancer. About 1,320 participants will be randomly assigned to either have their treatment based on the blood test results or receive st…

This study looks at whether exercise can help prevent cancer from coming back in adults who have already had cancer. Researchers will review data from 1,000 cancer survivors to compare those who exercise with those who don't. The goal is to see if staying active is linked to bett…

This study is testing a new approach called xDRIVE that combines lab tests on tumor samples with artificial intelligence to suggest personalized cancer treatments. It involves 210 Florida patients with cancers that have come back or not responded to standard therapy, including ch…

This study is developing and testing two new kits that aim to predict if early-stage lung cancer will come back after surgery. Researchers will use protein markers from tumor samples and blood tests to identify high-risk patients. The goal is to help doctors decide who needs more…