RECURRENCE

This study enrolls healthy relatives of patients with advanced HPV-related head and neck cancer. Donors receive a therapeutic HPV vaccine to boost their immune cells against HPV. These cells are then collected and used in a separate transplant or cell infusion to treat the patien…

This study tests a single injection of a virus (DNX-2401) directly into brain tumors in children and young adults whose cancer has come back or not responded to treatment. The goal is to see if the virus can shrink tumors and help patients live longer. 39 participants will receiv…

This study tests a new cell therapy called AB-2100 for people with advanced or metastatic clear-cell kidney cancer that has come back after other treatments. About 37 to 130 participants will receive the therapy to see if it is safe and shrinks tumors. The goal is to control the …

This study tests if bevacizumab, a drug that blocks blood vessel growth, can help adults with recurrent respiratory papillomatosis (RRP) go longer between surgeries. RRP causes wart-like growths in the airways that often return after removal. About 21 participants will receive th…

This study aims to find brain-based markers that predict whether depression will return in older adults. Researchers will measure stress reactions and brain network activity in 210 people aged 60 and older, some currently depressed and some in remission. The goal is to understand…

This study follows 250 people who have recovered from an eating disorder. Nurses will call them once a year for three years to check on their progress and spot any signs of relapse early. The goal is to learn how often relapses happen and what factors might increase the risk.