RECTAL CARCINOMA
Clinical trials for RECTAL CARCINOMA explained in plain language.
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MRI-Guided therapy could spare rectal cancer patients unnecessary surgery
Disease control Recruiting nowThis study is for people with locally advanced rectal cancer. It aims to see if using MRI scans early after chemotherapy can help doctors choose the best next step: surgery right away or more chemo with radiation before surgery. The goal is to improve cancer control and reduce si…
Matched conditions: RECTAL CARCINOMA
Phase: PHASE2, PHASE3 • Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle • Aim: Disease control
Last updated May 26, 2026 05:43 UTC
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New drug shows promise in shrinking HER2+ colorectal tumors before surgery
Disease control Recruiting nowThis study tests a drug called zanidatamab given before surgery to people with HER2-positive colorectal cancer. The goal is to see if the drug can shrink or eliminate tumors, making surgery more effective. About 38 adults with early-stage cancer will take part, and researchers wi…
Matched conditions: RECTAL CARCINOMA
Phase: PHASE2 • Sponsor: Emory University • Aim: Disease control
Last updated May 22, 2026 14:02 UTC
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New CT scanner could rival MRI for rectal cancer staging
Diagnosis Recruiting nowThis study looks at whether a new type of CT scanner (PCD-CT) can determine how far rectal cancer has grown as accurately as MRI. About 200 adults with rectal cancer will get both scans, and doctors will compare the results. If PCD-CT works as well, it could offer a faster or mor…
Matched conditions: RECTAL CARCINOMA
Sponsor: Mayo Clinic • Aim: Diagnosis
Last updated May 26, 2026 05:55 UTC
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Enema program may ease bowel troubles after rectal cancer surgery
Symptom relief Recruiting nowThis study tests whether a bowel management program using a retrograde enema works better than standard medical care for people with bowel control problems after rectal cancer surgery. About 80 adults with moderate to severe symptoms who haven't improved with standard care will t…
Matched conditions: RECTAL CARCINOMA
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 26, 2026 05:58 UTC
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Can a hormone cream ease Radiation's vaginal side effects?
Symptom relief Recruiting nowThis study tests whether a vaginal DHEA cream can help women who have had radiation for gynecologic, anal, or rectal cancer. Radiation often causes vaginal dryness, burning, and pain. The trial will enroll 25 women to see if the cream is safe and tolerable, and if it improves vag…
Matched conditions: RECTAL CARCINOMA
Phase: PHASE2 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 26, 2026 05:46 UTC
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New algorithm aims to keep chemo on schedule for GI cancer patients
Symptom relief Recruiting nowThis study tests a new tool called the PAGODA algorithm to help doctors adjust chemotherapy doses proactively. The goal is to reduce unplanned treatment delays in people with gastrointestinal cancers receiving FOLFOX chemotherapy. About 420 participants will be randomly assigned …
Matched conditions: RECTAL CARCINOMA
Phase: NA • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Symptom relief
Last updated May 26, 2026 05:43 UTC
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New imaging tracer could light up tumors for better detection
Knowledge-focused Recruiting nowThis early-phase study tests whether a new radioactive tracer can help doctors see tumors on PET/CT scans. About 32 adults with different solid tumors will receive a single injection of the tracer. The goal is to understand where the tracer goes in the body, how it is cleared, an…
Matched conditions: RECTAL CARCINOMA
Phase: EARLY_PHASE1 • Sponsor: Var2 Pharmaceuticals • Aim: Knowledge-focused
Last updated May 20, 2026 11:54 UTC