PROGRESSIVE MULTIPLE SCLEROSIS
Clinical trials for PROGRESSIVE MULTIPLE SCLEROSIS explained in plain language.
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Can a cancer drug stall MS progression? phase 3 trial halted
Disease control TerminatedThis phase 3 study tested whether the oral drug masitinib could slow disability worsening in people with progressive multiple sclerosis (MS) who are no longer having relapses. About 800 adults with primary or secondary progressive MS were randomly assigned to receive masitinib or…
Matched conditions: PROGRESSIVE MULTIPLE SCLEROSIS
Phase: PHASE3 • Sponsor: AB Science • Aim: Disease control
Last updated May 26, 2026 03:55 UTC
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Could CAR t cells slow progressive MS? early trial underway
Disease control OngoingThis early-phase study tests a new treatment called KYV-101 in 10 people with progressive multiple sclerosis (MS) whose disease has not responded to standard therapies. The treatment uses a patient's own immune cells, modified to target and potentially calm the immune attack on t…
Matched conditions: PROGRESSIVE MULTIPLE SCLEROSIS
Phase: PHASE1 • Sponsor: Bruce Cree • Aim: Disease control
Last updated May 26, 2026 03:54 UTC
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Could a short-course pill slow disability in advanced MS?
Disease control OngoingThis study tests whether cladribine tablets, given over two years, can protect hand function in people with advanced multiple sclerosis (MS). About 204 adults with significant disability (EDSS 6.5-8.5) will receive either cladribine or a placebo. The goal is to see if the drug sl…
Matched conditions: PROGRESSIVE MULTIPLE SCLEROSIS
Phase: PHASE2, PHASE3 • Sponsor: Queen Mary University of London • Aim: Disease control
Last updated May 26, 2026 03:52 UTC
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Can your own stem cells fix MS nerve damage?
Disease control OngoingThis early-phase study tests whether a patient's own stem cells, injected into the spinal fluid, can repair nerve damage caused by progressive multiple sclerosis (MS). The trial involves 18 adults with secondary or primary progressive MS. Researchers will measure changes in nerve…
Matched conditions: PROGRESSIVE MULTIPLE SCLEROSIS
Phase: PHASE1, PHASE2 • Sponsor: Haukeland University Hospital • Aim: Disease control
Last updated May 18, 2026 12:04 UTC
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Could a light bulb ease MS fatigue? new trial launches
Symptom relief ENROLLING_BY_INVITATIONThis early-stage study tests whether a special light therapy is safe and tolerable for people with progressive multiple sclerosis who experience fatigue. About 20 participants will receive the light treatment, and researchers will monitor side effects and measure changes in fatig…
Matched conditions: PROGRESSIVE MULTIPLE SCLEROSIS
Phase: PHASE1 • Sponsor: University of Texas Southwestern Medical Center • Aim: Symptom relief
Last updated May 19, 2026 11:49 UTC