PROGRESSIVE MULTIPLE SCLEROSIS
Clinical trials for PROGRESSIVE MULTIPLE SCLEROSIS explained in plain language.
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CAR-T cells take on progressive MS: early trial launches
Disease control Recruiting nowThis early-phase trial tests a single dose of YTB323, a CAR-T cell therapy, in 28 adults with non-active progressive multiple sclerosis. The study aims to check safety and track disability changes over time. Participants must be 18–60 and able to undergo lumbar punctures and MRIs…
Matched conditions: PROGRESSIVE MULTIPLE SCLEROSIS
Phase: PHASE1, PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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New combo therapy aims to slow progressive MS disability
Disease control Recruiting nowThis study tests whether adding a new drug (RO7268489) to the standard MS treatment ocrelizumab can slow disability progression in adults with progressive multiple sclerosis. About 360 participants will receive either the new drug or a placebo, and researchers will track walking …
Matched conditions: PROGRESSIVE MULTIPLE SCLEROSIS
Phase: PHASE2 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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Could CAR T-Cells halt progressive MS? early trial launches
Disease control Recruiting nowThis early-stage trial is testing a new treatment called obe-cel, a type of cell therapy (CAR T-cell), for people with progressive multiple sclerosis (MS) that hasn't improved with standard treatments. The main goal is to see if it's safe, but researchers will also look for any s…
Matched conditions: PROGRESSIVE MULTIPLE SCLEROSIS
Phase: PHASE1 • Sponsor: Autolus Limited • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Can a VR forest lift your mood? new study tests nature walks for MS depression
Symptom relief Recruiting nowThis study explores whether using a virtual reality headset to experience nature scenes can help reduce depression in people with progressive multiple sclerosis. About 40 participants will use the Apple Vision Pro at home for short sessions over 8 weeks. The goal is to see if thi…
Matched conditions: PROGRESSIVE MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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New brain scan study aims to improve MS diagnosis and monitoring
Knowledge-focused Recruiting nowThis study looks at how the brain uses sugar (glucose) in people with multiple sclerosis (MS) compared to healthy volunteers. Researchers will use a special PET scan to measure brain activity and compare it with MRI scans and blood tests. The goal is to find better ways to diagno…
Matched conditions: PROGRESSIVE MULTIPLE SCLEROSIS
Phase: PHASE4 • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC