PROGRESSIVE MULTIPLE SCLEROSIS
Clinical trials for PROGRESSIVE MULTIPLE SCLEROSIS explained in plain language.
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Brain scans reveal Ocrelizumab's impact on MS inflammation
Disease control CompletedThis study looked at how ocrelizumab, a standard MS medication, changes brain inflammation in 22 people with multiple sclerosis. Researchers used special PET and MRI scans to measure inflammation before and after one year of treatment. The goal was to see if the drug reduces harm…
Matched conditions: PROGRESSIVE MULTIPLE SCLEROSIS
Phase: PHASE4 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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New brain scans may reveal why nerves die in MS
Knowledge-focused CompletedThis study used advanced MRI scans to look at energy use in the brains of 40 people with multiple sclerosis and 15 healthy volunteers. The goal was to see if energy problems in brain cells can predict nerve damage over two years. Researchers hope this will help understand how MS …
Matched conditions: PROGRESSIVE MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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Eye camera spots hidden inflammation in MS patients
Knowledge-focused CompletedThis study used a special eye camera (adaptive optics) to look at blood vessel inflammation in the retina of 50 people with multiple sclerosis (MS) and healthy volunteers. The goal was to see if this inflammation differs between MS types and could serve as an early marker of dise…
Matched conditions: PROGRESSIVE MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Blood tests may help unravel mysterious MS variants
Knowledge-focused CompletedThis completed study measured two proteins in the blood—neurofilament light chain and GFAP—that can signal nerve damage. Researchers compared 15 people with atypical MS, 30 with typical MS, and 15 healthy controls to see if these markers differ. The goal was to better understand …
Matched conditions: PROGRESSIVE MULTIPLE SCLEROSIS
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC