PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Clinical trials for PROGNOSTIC STAGE IV BREAST CANCER AJCC V8 explained in plain language.
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New drug combo targets breast cancer in the brain
Disease control OngoingThis study tests a drug called sacituzumab govitecan in 44 people with HER2-negative breast cancer that has spread to the brain. The drug works like a smart bomb, attaching to a protein on cancer cells and delivering chemotherapy directly to them. The goal is to see if it can shr…
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated May 26, 2026 04:37 UTC
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Cancer-Killing virus trial launches for Hard-to-Treat breast cancer
Disease control OngoingThis early-phase trial tests a new treatment for people with metastatic triple-negative breast cancer, a type that has spread and is hard to treat. The treatment uses a specially designed virus that is injected directly into tumors to infect and break them down. The main goal is …
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 22, 2026 14:01 UTC
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New drug cocktail shows promise in shrinking HER2+ breast tumors before surgery
Disease control OngoingThis study tests a combination of targeted drugs (ribociclib, tucatinib, trastuzumab) with or without hormone therapy (fulvestrant) for HER2-positive breast cancer. In the first part, it checks safety in patients whose cancer has spread. In the second part, it compares this combo…
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated May 20, 2026 11:55 UTC
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New drug combo targets BRCA cancers in early trial
Disease control OngoingThis early-phase trial tests a combination of two drugs—niraparib (a PARP inhibitor) and dostarlimab (an immunotherapy)—in people with BRCA-mutated breast, pancreas, or ovarian cancers that have spread or cannot be surgically removed. The goal is to see if the combo can shrink tu…
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: University of Washington • Aim: Disease control
Last updated May 18, 2026 12:13 UTC
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New combo therapy aims to turn tumors against themselves in advanced cancer patients
Disease control OngoingThis early-phase study tests whether a mix of drugs and targeted radiation can help the immune system recognize and attack hard-to-treat solid tumors. About 14 adults with advanced melanoma, breast cancer, or other solid cancers that cannot be surgically removed will receive inje…
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: University of Southern California • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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Blood test may tame Chemo's nerve pain
Knowledge-focused TerminatedThis study looks at whether regularly measuring the amount of paclitaxel (a chemotherapy drug) in the blood can help doctors give the right dose to kill cancer while limiting nerve damage. About 22 adults with various solid tumors (like lung, breast, or ovarian cancer) will have …
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated May 26, 2026 04:45 UTC
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Video boosts cancer Patients' understanding of genetic tests
Knowledge-focused OngoingThis study looks at whether watching a short video can help people with metastatic cancer better understand tumor genomic testing. About 243 adults with advanced breast, lung, or other solid tumors will watch the video and answer questions before and after. The goal is to see if …
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 26, 2026 04:38 UTC
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New scan could improve how we track breast cancer in bones
Knowledge-focused OngoingThis study tests whether a special type of PET/CT scan (FDG-PET/CT) can better measure how well treatment is working in breast cancer that has spread to the bones. About 138 people with this type of cancer will get the scan before and after starting treatment. The goal is to see …
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Knowledge-focused
Last updated May 26, 2026 04:32 UTC
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Gene test may guide breast cancer treatment choices
Knowledge-focused OngoingThis study looks at whether testing tumor genes can help predict if HER2-negative breast cancer will respond to standard treatments like chemotherapy or hormone therapy. About 1,100 people with early-stage breast cancer (stages I to III) will have their tumor samples analyzed. Th…
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated May 20, 2026 11:53 UTC