PRIMARY SCLEROSING CHOLANGITIS
Clinical trials for PRIMARY SCLEROSING CHOLANGITIS explained in plain language.
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First-in-Human test for new liver disease drug begins
Disease control Recruiting nowThis is an early safety study for a new drug called TAK-781. It will first test the drug in healthy volunteers to see if it is safe and how the body processes it. Then, a small group of people with a serious liver disease called primary sclerosing cholangitis (PSC) will receive a…
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Phase: PHASE1 • Sponsor: Takeda • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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Could a vitamin B12 derivative help tame a rare liver disease?
Disease control Recruiting nowThis study is testing whether an oral medication called BRS201 can help control primary sclerosing cholangitis (PSC), a rare liver disease. For 8 weeks, 28 participants will take either the study drug or a placebo pill in a random order to see if it can normalize a key liver enzy…
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Phase: PHASE2 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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New drug tested to protect transplanted livers
Disease control Recruiting nowThis early-stage study is testing the safety of an investigational drug called siplizumab in patients with autoimmune liver disease who are receiving a liver transplant. The drug is given right after surgery to help prevent the body's immune system from attacking the new liver. U…
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Phase: PHASE1 • Sponsor: Elizabeth C. Verna • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Scientists launch major study to unravel mysteries of childhood liver disease
Knowledge-focused Recruiting nowThis study aims to learn more about a rare liver disease called Primary Sclerosing Cholangitis (PSC) in children and young adults. Researchers will observe up to 1,000 participants over time to understand how the disease progresses, how it affects daily life, and what factors mig…
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Sponsor: Arbor Research Collaborative for Health • Aim: Knowledge-focused
Last updated Apr 04, 2026 04:51 UTC
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Scientists launch deep dive to unlock mysteries of rare liver disease
Knowledge-focused Recruiting nowThis study aims to understand the biological causes of Primary Sclerosing Cholangitis (PSC), a rare and serious chronic liver disease. Researchers will collect extensive data from about 143 adults with PSC, including blood, tissue, and microbiome samples, to look for patterns in …
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Apr 04, 2026 04:51 UTC
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Scientists grow Mini-Livers from patient bile to crack disease code
Knowledge-focused Recruiting nowThis study aims to collect bile samples and medical information from people with Primary Sclerosing Cholangitis (PSC) and people without liver disease. Researchers will use these samples to grow tiny 3D liver-like structures called organoids in the lab. By studying these organoid…
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Apr 04, 2026 04:50 UTC
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Can a common pill unlock clues to a devastating liver disease?
Knowledge-focused Recruiting nowThis small, early study is testing if a cholesterol-lowering drug called rosuvastatin changes bile acids and gut bacteria in people with primary sclerosing cholangitis (PSC), a rare liver disease with no cure. The goal is to understand the biology of PSC better, which could help …
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Phase: EARLY_PHASE1 • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Apr 04, 2026 04:50 UTC
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Mayo clinic launches massive biobank to crack the code on rare liver diseases
Knowledge-focused Recruiting nowThis study is creating a large collection of blood, saliva, stool, and other samples from people with rare liver diseases and healthy volunteers. The goal is to help researchers better understand diseases like Primary Sclerosing Cholangitis (PSC) and Primary Biliary Cholangitis (…
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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Scientists hunt for gut bacteria clues in liver disease
Knowledge-focused Recruiting nowThis study aims to understand the connection between gut bacteria and several chronic liver diseases. Researchers will compare blood and stool samples from 3,000 adult patients with conditions like autoimmune hepatitis and fatty liver disease to samples from their healthy househo…
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Sponsor: Chungnam National University Hospital • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:16 UTC