PRIMARY SCLEROSING CHOLANGITIS
Clinical trials for PRIMARY SCLEROSING CHOLANGITIS explained in plain language.
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New drug shows promise for rare liver disease in early trial
Disease control CompletedThis study tested an experimental drug called PLN-74809 in 121 adults with primary sclerosing cholangitis (PSC) and suspected liver scarring. The main goal was to check the drug's safety and how the body processes it. Participants received different doses of the drug or a placebo…
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Phase: PHASE2 • Sponsor: Pliant Therapeutics, Inc. • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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Could a common arthritis drug ease a rare liver disease?
Disease control CompletedThis study tested whether sulfasalazine, a drug used for arthritis and inflammatory bowel disease (IBD), can help people with primary sclerosing cholangitis (PSC), a rare liver condition. About 32 adults with both PSC and IBD took either sulfasalazine or a placebo for several mon…
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Phase: PHASE2 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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New MRI scan for liver disease put to the test
Knowledge-focused CompletedThis study checked if a special MRI scan called LiverMultiScan gives the same results when repeated on the same machine or on different machines. 61 adults with various liver diseases were scanned multiple times. The goal was to see if the scan reliably measures liver fat, iron, …
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Sponsor: Perspectum • Aim: Knowledge-focused
Last updated May 26, 2026 11:13 UTC
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Can a special diet improve gut health in PSC patients?
Knowledge-focused CompletedThis study looked at how two different diets affect people with primary sclerosing cholangitis (PSC), a rare liver disease. Twenty adults were randomly assigned to follow either a vegan/low-sulfur diet or the specific carbohydrate diet for 8 weeks. Researchers measured changes in…
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC