PRADER-WILLI SYNDROME
Clinical trials for PRADER-WILLI SYNDROME explained in plain language.
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New program aims to help Prader-Willi patients keep weight off
Disease control CompletedThis study tested a 5-week hospital program combining exercise, nutrition advice, and education for adults with Prader-Willi syndrome. The goal was to help patients stabilize or lower their body mass index (BMI) for 6 months after leaving the hospital. 128 participants were rando…
Matched conditions: PRADER-WILLI SYNDROME
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated May 26, 2026 11:28 UTC
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Growth hormone study aims to improve body composition in Prader-Willi syndrome
Disease control CompletedThis study tested the safety and effectiveness of somatropin, a growth hormone, in 33 Japanese people with Prader-Willi syndrome. The goal was to see if the treatment could improve lean body mass (muscle) over 12 months. Participants included both children and adults, and the stu…
Matched conditions: PRADER-WILLI SYNDROME
Phase: PHASE3 • Sponsor: Pfizer • Aim: Disease control
Last updated May 26, 2026 11:27 UTC
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New hope for wakefulness: drug fights sleepiness in rare genetic disorder
Symptom relief CompletedThis study tested a medication called pitolisant to see if it could safely reduce severe daytime sleepiness in people with Prader-Willi syndrome, a genetic condition. 65 participants aged 6 to 65 took either the drug or a placebo for 11 weeks. The main goal was to measure changes…
Matched conditions: PRADER-WILLI SYNDROME
Phase: PHASE2 • Sponsor: Harmony Biosciences Management, Inc. • Aim: Symptom relief
Last updated May 26, 2026 11:17 UTC
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Can the 'love hormone' ease behavior issues in Prader-Willi syndrome?
Symptom relief CompletedThis study tested whether oxytocin nasal spray can improve behavior and social skills in adults with Prader-Willi syndrome, a genetic condition. Fifty participants received the spray to see if it reduces problem behaviors and improves quality of life. The goal was to find a new w…
Matched conditions: PRADER-WILLI SYNDROME
Phase: PHASE2, PHASE3 • Sponsor: University Hospital, Toulouse • Aim: Symptom relief
Last updated May 26, 2026 11:17 UTC
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Hormone clues may explain why Prader-Willi babies go from feeding struggles to obesity
Knowledge-focused CompletedThis study followed 215 infants with Prader-Willi syndrome and a control group to measure hormones that control appetite and growth during the first four years of life. The goal was to understand why children with PWS switch from poor feeding in infancy to extreme hunger and obes…
Matched conditions: PRADER-WILLI SYNDROME
Phase: NA • Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated May 26, 2026 11:26 UTC