Hormone study aims to unlock Prader-Willi feeding mystery
NCT ID NCT02529085
First seen Apr 11, 2026 · Last updated Jun 23, 2026 · Updated 11 times
Summary
This completed study looked at how appetite-regulating hormones change in infants with Prader-Willi syndrome during the first four years of life. Researchers collected blood samples from 215 infants to understand why they switch from poor feeding to severe overeating and obesity. The goal is to identify the underlying causes and pave the way for future treatments.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Department of Endocrinology / University Children's Hospital
Essen, Germany
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Department of Pediatrics / Division of Endocrinology
Toulouse, Haute-Garonne, 31000, France
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Department of Pediatrics / Division of Endocrinology / Erasmus University Medical Center / Sophia Children's Hospital Rotterdam
Rotterdam, 3015 GJ, Netherlands
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Karolinska University Hospital
Stockholm, Sweden
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Metabolic & Molecular Imaging Group / MRC Clinical Sciences Centre / Imperial College London / Hammersmith Hospital
London, W12 0NN, United Kingdom
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Unité d'Endocrinologie Pédiatrique / Université Catholique de Louvain
Brussels, 1200, Belgium
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help explain why children with Prader-Willi syndrome go from poor feeding to severe overeating, pointing toward future treatments.
What could go wrong
This is an observational study, not a treatment trial. It may not directly lead to therapies, and results may not apply to all patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.