POSTPARTUM HEMORRHAGE

This study tests a set of simple steps called 'Rule of THUMB' to help doctors better prevent, spot, and treat heavy bleeding during and after C-sections. About 2400 women having C-sections in African hospitals will take part. The goal is to see if this care plan improves safety a…

This study looks at whether draining the umbilical cord after delivery can lower the chance of severe bleeding (postpartum hemorrhage) in new mothers. About 400 women having a vaginal birth will be randomly assigned to either have cord drainage or not. Researchers will measure bl…

This study is testing the lowest effective dose of oxytocin to keep the uterus contracted after a C-section in women who have been in labor. Oxytocin is a drug commonly used to prevent postpartum hemorrhage. The trial will enroll 40 women and adjust the dose based on each previou…

This study tests a device called KOKO, which uses gentle suction inside the uterus to remove excess blood and help the uterus contract, stopping heavy bleeding after childbirth. About 72 women who experience significant blood loss within 24 hours of delivery will be enrolled. The…

This study looks back at medical records of 648 women who had heavy bleeding after a C-section. Researchers want to see how often the drug tranexamic acid (TXA) was given over the years, and whether more use led to better outcomes like less blood loss or fewer transfusions. The g…

This study compares a serious game-based training to traditional teaching for nursing students learning to manage postpartum hemorrhage (heavy bleeding after childbirth). About 70 third-year nursing students will be split into two groups: one gets the game training plus standard …

This study looks at how three common blood pressure medications (ephedrine, phenylepinephrine, and norepinephrine) affect the ability of the uterus to contract after a C-section in women with type 2 or gestational diabetes. Researchers will take small tissue samples from the uter…

This study uses small samples of uterine tissue from 32 women having planned C-sections to test which backup drug best contracts the uterus after carbetocin has been given. The goal is to improve treatment for severe bleeding after childbirth. The research is done in the lab, not…