PLEXIFORM NEUROFIBROMA
Clinical trials for PLEXIFORM NEUROFIBROMA explained in plain language.
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New hope for kids with tough cancers: first pediatric trial of promising drug duo
Disease control Recruiting nowThis study is testing the safety of a new two-drug combination (avutometinib and defactinib) for children and young adults (ages 3-30) whose solid tumors have come back or stopped responding to standard treatments. The main goal is to find the highest dose that is safe and causes…
Matched conditions: PLEXIFORM NEUROFIBROMA
Phase: PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Could a simple blood test spot deadly cancer sooner?
Diagnosis Recruiting nowThis study aims to see if a 'liquid biopsy' blood test can find a dangerous cancer called MPNST earlier in adults with Neurofibromatosis Type 1 (NF1). Researchers will compare the blood test results to the current standard methods of doctor exams and imaging scans over five years…
Matched conditions: PLEXIFORM NEUROFIBROMA
Sponsor: David Miller • Aim: Diagnosis
Last updated Apr 03, 2026 21:26 UTC
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Could early drug stop debilitating tumors before they start?
Prevention Recruiting nowThis study is testing if starting a drug called selumetinib early can prevent dangerous tumors from growing and causing serious problems in young children with neurofibromatosis type 1 (NF1). It will enroll 200 children aged 1 to 8 years who have these tumors in high-risk areas b…
Matched conditions: PLEXIFORM NEUROFIBROMA
Phase: PHASE2 • Sponsor: University of Alabama at Birmingham • Aim: Prevention
Last updated Apr 03, 2026 14:41 UTC