PLEXIFORM NEUROFIBROMA
Clinical trials for PLEXIFORM NEUROFIBROMA explained in plain language.
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New pill could shrink nerve tumors in NF1 patients
Disease control Recruiting nowThis study tests a new drug called TQ-B3234 in people with neurofibromatosis type 1 who have painful, inoperable nerve tumors. The goal is to see if the drug can shrink these tumors better than a placebo after 24 weeks. About 177 adults will take part, and the drug is taken as a …
Matched conditions: PLEXIFORM NEUROFIBROMA
Phase: PHASE3 • Sponsor: Chia Tai Tianqing Pharmaceutical Group Co., Ltd. • Aim: Disease control
Last updated May 26, 2026 05:25 UTC
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New hope for kids with recurrent tumors: drug combo enters safety trial
Disease control Recruiting nowThis early-stage study is testing a combination of two drugs, avutometinib and defactinib, in children and young adults (ages 3 to 30) with solid tumors that have returned or not responded to treatment. The main goal is to find a safe dose and check for side effects. The study is…
Matched conditions: PLEXIFORM NEUROFIBROMA
Phase: PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 22, 2026 13:50 UTC
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Early drug use may stop tumors before they cause harm in kids with NF1
Prevention Recruiting nowThis study tests whether giving selumetinib early to children aged 1 to 8 with NF1 can prevent plexiform neurofibromas from growing and causing serious issues like pain or blindness. Half the children will receive the drug, while the other half will be observed. The goal is to se…
Matched conditions: PLEXIFORM NEUROFIBROMA
Phase: PHASE2 • Sponsor: University of Alabama at Birmingham • Aim: Prevention
Last updated May 22, 2026 13:53 UTC
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Blood test could spot rare cancer in NF1 patients years earlier
Knowledge-focused Recruiting nowThis study looks at whether a blood test (liquid biopsy) can find a rare cancer called MPNST earlier than current methods in adults with Neurofibromatosis Type 1 (NF1). About 1,000 participants will give blood samples and complete surveys every six months for five years. The goal…
Matched conditions: PLEXIFORM NEUROFIBROMA
Sponsor: David Miller • Aim: Knowledge-focused
Last updated May 20, 2026 11:54 UTC