PLEXIFORM NEUROFIBROMA
Clinical trials for PLEXIFORM NEUROFIBROMA explained in plain language.
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New hope for kids with tough cancers: first pediatric trial of promising drug duo
Disease control Recruiting nowThis study is testing the safety of a new two-drug combination (avutometinib and defactinib) for children and young adults (ages 3-30) whose solid tumors have come back or stopped responding to standard treatments. The main goal is to find the highest dose that is safe and causes…
Matched conditions: PLEXIFORM NEUROFIBROMA
Phase: PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Simple blood test could spot dangerous nerve tumors sooner
Diagnosis Recruiting nowThis study is testing whether a 'liquid biopsy'—a simple blood test—can detect a dangerous type of nerve tumor (MPNST) earlier than current methods in adults with Neurofibromatosis Type 1 (NF1). Researchers will follow 1,000 adults with NF1 for five years, collecting blood sample…
Matched conditions: PLEXIFORM NEUROFIBROMA
Sponsor: David Miller • Aim: Diagnosis
Last updated Mar 31, 2026 12:11 UTC
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Could early drug stop debilitating tumors in kids before damage is done?
Prevention Recruiting nowThis study is testing if giving the drug selumetinib early can prevent dangerous, non-cancerous nerve tumors from growing and causing serious problems like blindness or nerve damage in young children with neurofibromatosis type 1 (NF1). It will enroll up to 200 children aged 1 to…
Matched conditions: PLEXIFORM NEUROFIBROMA
Phase: PHASE2 • Sponsor: University of Alabama at Birmingham • Aim: Prevention
Last updated Mar 27, 2026 12:37 UTC