PLEXIFORM NEUROFIBROMA
Clinical trials for PLEXIFORM NEUROFIBROMA explained in plain language.
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New pill could shrink nerve tumors in NF1 patients
Disease control Recruiting nowThis study tests a new drug called TQ-B3234 in adults with neurofibromatosis type 1 who have painful nerve tumors that cannot be removed by surgery. The goal is to see if the drug can shrink these tumors better than a placebo. About 177 participants will take either the drug or a…
Matched conditions: PLEXIFORM NEUROFIBROMA
Phase: PHASE3 • Sponsor: Chia Tai Tianqing Pharmaceutical Group Co., Ltd. • Aim: Disease control
Last updated May 11, 2026 20:52 UTC
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New hope for kids with resistant tumors: drug combo enters safety trial
Disease control Recruiting nowThis early-phase study tests a combination of two drugs, avutometinib and defactinib, in children and young adults (ages 3 to 30) with solid tumors that have returned or not responded to treatment. The main goal is to find a safe dose with manageable side effects. The drugs targe…
Matched conditions: PLEXIFORM NEUROFIBROMA
Phase: PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 06, 2026 16:15 UTC
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Early drug treatment may stop NF1 tumors before they cause harm
Prevention Recruiting nowThis study tests whether giving selumetinib early to children with NF1 (ages 1 to 8) can prevent nerve tumors from growing and causing serious problems like blindness or nerve damage. About 200 children with no current symptoms but tumors in risky locations will either receive se…
Matched conditions: PLEXIFORM NEUROFIBROMA
Phase: PHASE2 • Sponsor: University of Alabama at Birmingham • Aim: Prevention
Last updated May 06, 2026 16:14 UTC
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Blood test could spot rare cancer early in NF1 patients
Knowledge-focused Recruiting nowThis study is testing whether a blood test (liquid biopsy) can detect a rare but serious cancer called MPNST earlier than current methods in adults with Neurofibromatosis Type 1 (NF1). Researchers will collect blood samples and surveys from 1,000 participants every six months for…
Matched conditions: PLEXIFORM NEUROFIBROMA
Sponsor: David Miller • Aim: Knowledge-focused
Last updated May 12, 2026 13:41 UTC