Periprosthetic joint infection
Clinical trials for Periprosthetic joint infection explained in plain language.
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Bone-Delivered antibiotics could spare joint infection patients from repeat surgeries
Disease control By invitation onlyThis study tests whether giving antibiotics directly into the bone during a standard cleaning surgery can better control joint infections and reduce the need for additional major surgeries. About 100 adults with infected knee or hip replacements will receive this targeted antibio…
Matched conditions: PERIPROSTHETIC JOINT INFECTION
Phase 4 • Sponsor: OrthoCarolina Research Institute, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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One surgery enough? trial tests if extra procedure helps fight joint infections
Disease control By invitation onlyThis study compares two standard treatments for acute infection after hip or knee replacement: a single surgery to clean the joint versus two planned surgeries. About 490 participants will be randomly assigned to one approach. The goal is to see which method better prevents the n…
Matched conditions: PERIPROSTHETIC JOINT INFECTION
Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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Joint infection study pulled before starting: antibiotic duration question remains unanswered
Knowledge-focused CancelledThis study aimed to find the best length of time for patients to take antibiotics after surgery for an infected joint replacement. It planned to compare different antibiotic durations to see which works best to prevent the infection from coming back and to avoid antibiotic resist…
Matched conditions: PERIPROSTHETIC JOINT INFECTION
Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Bone cancer implant infections under the microscope
Knowledge-focused By invitation onlyThis study looks at why people with bone cancer (skeletal sarcoma) get more infections after joint replacement surgery than those with arthritis. Researchers will collect tissue and blood samples from 40 patients to compare immune and bacterial factors. The goal is to understand …
Matched conditions: PERIPROSTHETIC JOINT INFECTION
Sponsor: Vastra Gotaland Region • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC