Joint infection study pulled before starting: antibiotic duration question remains unanswered
NCT ID NCT05495815
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aimed to find the best length of time for patients to take antibiotics after surgery for an infected joint replacement. It planned to compare different antibiotic durations to see which works best to prevent the infection from coming back and to avoid antibiotic resistance. However, the study was withdrawn before enrolling any participants, so no results are available.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Expected to start
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Dec 2024
An estimate. Start dates often move.
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * over 18 years-old * underwent DAIR with modular component exchange for acute TJA PJI, as defined by Musculoskeletal Infection Society Criteria, with symptom duration less than 4 weeks * on postoperative oral SAT for at least 3 months Exclusion Criteria: * underwent aseptic revision surgery * had one-stage, 1.5-stage, or two-stage revision surgery * did not have postoperative SAT * did not have follow-up that allowed for evaluation of SAT sequelae
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Maryland
Baltimore, Maryland, 21201, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New nail aims to stop ankle infections in their tracks
- Bone-Delivered antibiotics could spare joint infection patients from repeat surgeries
- Swiss study aims to crack the code on joint infection cures
- Could a simple antibiotic combo stop stubborn joint infections?