PERIPHERAL VASCULAR DISEASES

This large study is testing whether using automated carbon dioxide injections, instead of standard iodine-based dye, during leg artery procedures can better protect patients' kidneys. It focuses on nearly 2,000 people with poor circulation and a moderate risk of kidney damage fro…

This study is testing whether a computer alert in the medical record system can help doctors prescribe cholesterol-lowering medications to patients with peripheral artery disease (PAD) who are not currently on treatment. The alert reminds both doctors and patients about guideline…

This early-stage study is testing if a single dose of the drug diroximel fumarate (Vumerity) can improve blood vessel function and walking capacity in people with peripheral artery disease (PAD). Researchers will give 20 participants either the drug or a placebo and measure chang…

This study is collecting real-world information on how well approved drug-coated devices work for treating blocked arteries in the legs. It will follow 5,000 patients who receive these devices as part of their regular medical care. The goal is to understand treatment outcomes, sa…

This study aims to collect real-world safety and performance data on a range of BALT medical devices used to treat conditions like brain aneurysms and strokes. It will enroll up to 10,000 patients who have already received or will receive these devices as part of their standard c…

This study aims to understand how different types of exercise training affect blood vessel function. It will compare healthy individuals with people who have post-traumatic stress disorder (PTSD) or generalized anxiety disorder (GAD). Researchers will measure blood vessel health …

This study aims to understand how exercise training might improve blood vessel function in people with post-traumatic stress disorder (PTSD) or generalized anxiety disorder (GAD). Researchers will test 720 participants, including healthy individuals and those with these mental he…

This study aims to understand how different types of weightlifting exercise affect blood vessel function. Researchers will compare healthy adults to those with post-traumatic stress disorder (PTSD) or generalized anxiety disorder (GAD). Participants will complete various tests an…

This study aims to use MRI scans to identify which artery blockages in the legs are most difficult to treat with standard procedures. Researchers will scan patients before their artery-opening procedures and test different medical devices on donated limbs to see which cause less …