PERIAPICAL PERIODONTITIS
Clinical trials for PERIAPICAL PERIODONTITIS explained in plain language.
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New antibiotic paste may spare kids from painful tooth procedures
Disease control CompletedThis study tested a less invasive method called LSTR, which uses an antibiotic paste to clean infected baby molars, against the standard pulpectomy (like a root canal). 110 children aged 4 to 10 took part, and their teeth were checked for healing over 12 months. The goal was to s…
Matched conditions: PERIAPICAL PERIODONTITIS
Phase: NA • Sponsor: taymour abuawwad • Aim: Disease control
Last updated Jun 17, 2026 12:09 UTC
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New dental technique helps regrow roots in young teeth
Disease control CompletedThis study tested three different materials (blood clot, platelet-rich fibrin, and concentrated growth factor) combined with two types of rinses to help regrow root tissue in 30 immature permanent teeth with dead nerves. Participants aged 9 to 25 were followed for 12 months using…
Matched conditions: PERIAPICAL PERIODONTITIS
Phase: NA • Sponsor: Kahramanmaras Sutcu Imam University • Aim: Disease control
Last updated Jun 15, 2026 18:57 UTC
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New tooth-cleaning methods could speed healing of serious infections
Symptom relief CompletedThis study looked at five different methods for cleaning infected root canals in 132 people with large tooth infections. The goal was to see which technique helps the infection heal best by reducing the size of the infection site on X-rays. The methods included manual cleaning, u…
Matched conditions: PERIAPICAL PERIODONTITIS
Phase: NA • Sponsor: Recep Tayyip Erdogan University • Aim: Symptom relief
Last updated Jun 17, 2026 12:04 UTC
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Root canal showdown: one visit or two? new study has answers
Symptom relief CompletedThis study looked at whether a root canal for an infected tooth with an abscess can be done in one visit or needs two visits. 59 adults were followed for a year to see how well the infection healed. The goal was to find out which approach works better for clearing the infection a…
Matched conditions: PERIAPICAL PERIODONTITIS
Phase: NA • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Jun 15, 2026 19:05 UTC
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Precision dental surgery boosts healing and comfort
Symptom relief CompletedThis study tested a more precise dental surgery for people with persistent root infections after standard treatment. Using a 3D-printed guide, surgeons aimed to remove infected tissue more accurately, reduce surgery time, and improve quality of life. The trial involved 70 adults …
Matched conditions: PERIAPICAL PERIODONTITIS
Phase: NA • Sponsor: Postgraduate Institute of Dental Sciences Rohtak • Aim: Symptom relief
Last updated Jun 11, 2026 12:12 UTC
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Tooth infection study reveals key inflammation clues
Knowledge-focused CompletedThis study looked at 185 people to compare inflammation markers in those with tooth infections (apical periodontitis), gum disease (chronic periodontitis), and healthy gums. Researchers measured substances like TNF-α and PGE2 in blood and gum fluid. The goal was to better underst…
Matched conditions: PERIAPICAL PERIODONTITIS
Phase: NA • Sponsor: Istanbul Medipol University Hospital • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:55 UTC