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New dental technique helps regrow roots in young teeth

NCT ID NCT07265804

Disease control Sponsor: Kahramanmaras Sutcu Imam University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested three different materials (blood clot, platelet-rich fibrin, and concentrated growth factor) combined with two types of rinses to help regrow root tissue in 30 immature permanent teeth with dead nerves. Participants aged 9 to 25 were followed for 12 months using special X-rays to measure root growth, tip closure, and healing of infection. The goal was to find the best combination to save teeth that would otherwise be lost.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Oct 2023

Finished

Oct 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

9 to 25 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Immature permanent teeth with open apices * Diagnosis of pulp necrosis * Radiographic evidence of periapical pathology * Teeth suitable for isolation and restoration * Patients aged 9 to 25 years * No systemic diseases that contraindicate dental treatment * Willingness to attend follow-up visits * Signed informed consent by patient or guardian Exclusion Criteria: * Teeth with root fractures * Teeth with severe canal curvature (\>30°) * Teeth with advanced root resorption * Periodontal pocket depth \>3 mm * Previous endodontic treatment or retreatment * Pregnancy * Use of antibiotics or analgesics within the last 7 days * Nonrestorable crowns * Uncooperative patients unable to attend follow-up

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Conditions

The condition(s) this trial relates to.

dental pulp necrosis isolated spina bifida periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Immature permanent teeth Open apex Periapical periodontitis Procedure Pulp necrosis

Contacts and locations

Locations

  • Kahramanmaraş Sütçü İmam University, Faculty of Dentistry

    Kahramanmaraş, 46010, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.