PELVIC ORGAN PROLAPSE (POP)
Clinical trials for PELVIC ORGAN PROLAPSE (POP) explained in plain language.
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Which surgery is better for uterine prolapse? major trial aims to find out.
Disease control Recruiting nowThis study compares two common surgeries for uterine prolapse: the Manchester procedure (which repairs and preserves the uterus) and vaginal hysterectomy (removing the uterus). About 426 women with symptomatic prolapse will be randomly assigned to one surgery and followed for up …
Matched conditions: PELVIC ORGAN PROLAPSE (POP)
Phase: NA • Sponsor: Tampere University Hospital • Aim: Disease control
Last updated May 26, 2026 05:47 UTC
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Mesh showdown: vaginal vs. robotic surgery for prolapse
Disease control Recruiting nowThis study compares two types of mesh surgery for women with pelvic organ prolapse, a condition where pelvic organs drop from their normal position. Researchers want to see if vaginal mesh surgery works as well as robotic-assisted abdominal mesh surgery and if it is just as safe.…
Matched conditions: PELVIC ORGAN PROLAPSE (POP)
Phase: NA • Sponsor: University of Sao Paulo General Hospital • Aim: Disease control
Last updated May 26, 2026 05:42 UTC
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Could a simple injection replace surgery for pelvic organ prolapse?
Disease control Recruiting nowThis study tests whether injecting poly-L-lactic acid (PLLA), an FDA-approved skin stimulant, into the vagina can strengthen tissue and treat a type of pelvic organ prolapse called cystocele (a bladder bulge into the vagina). The trial will compare PLLA injections to a placebo in…
Matched conditions: PELVIC ORGAN PROLAPSE (POP)
Phase: NA • Sponsor: Cassandra Kisby • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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Numbing injection may ease pain after keyhole pelvic surgery
Symptom relief Recruiting nowThis study tests whether a numbing injection (paracervical block) given during vNOTES surgery can lower pain after pelvic organ prolapse repair. About 58 women will be randomly assigned to receive either the numbing medicine or a placebo. The main goal is to measure pain levels 6…
Matched conditions: PELVIC ORGAN PROLAPSE (POP)
Phase: NA • Sponsor: Erkan Gol • Aim: Symptom relief
Last updated May 26, 2026 05:43 UTC
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New energy device may make ovary removal faster and less painful
Symptom relief Recruiting nowThis study tests if using an energy-based surgical device (LigaSure) to remove the fallopian tubes and ovaries during vaginal hysterectomy is safer and more effective than the standard knot-and-cut method. About 70 women with pelvic organ prolapse will take part. The goal is to s…
Matched conditions: PELVIC ORGAN PROLAPSE (POP)
Phase: NA • Sponsor: Wolfson Medical Center • Aim: Symptom relief
Last updated May 11, 2026 20:52 UTC
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Can early pelvic floor training prevent Post-Birth problems?
Knowledge-focused Recruiting nowThis study follows 380 women for one year after vaginal childbirth to see how pelvic floor muscles and tissues recover. It also tests whether early, personalized pelvic floor muscle training can improve symptoms like urine leakage, bowel issues, and vaginal bulging compared to st…
Matched conditions: PELVIC ORGAN PROLAPSE (POP)
Phase: NA • Sponsor: Vastra Gotaland Region • Aim: Knowledge-focused
Last updated May 26, 2026 05:53 UTC
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New model aims to predict bladder leak after pelvic surgery
Knowledge-focused Recruiting nowThis study looks at women having surgery for pelvic organ prolapse (when organs slip out of place). The goal is to find out who might develop new bladder leakage (stress urinary incontinence) after surgery. Researchers will follow 382 women for a year to build a risk prediction t…
Matched conditions: PELVIC ORGAN PROLAPSE (POP)
Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine • Aim: Knowledge-focused
Last updated May 26, 2026 05:44 UTC
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Wrist tracker reveals best recovery path after prolapse surgery
Knowledge-focused Recruiting nowThis study follows 288 women recovering from pelvic organ prolapse surgery. Participants wear a wrist accelerometer and complete a daily recovery questionnaire. Some receive routine post-op instructions, others get exercise-focused guidance. The goal is to see which approach help…
Matched conditions: PELVIC ORGAN PROLAPSE (POP)
Phase: NA • Sponsor: NICHD Pelvic Floor Disorders Network • Aim: Knowledge-focused
Last updated May 22, 2026 13:55 UTC