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Could a simple injection replace surgery for pelvic organ prolapse?

NCT ID NCT07544667

First seen Apr 23, 2026 · Last updated May 14, 2026 · Updated 5 times

Summary

This study tests whether injecting poly-L-lactic acid (PLLA), an FDA-approved skin stimulant, into the vagina can strengthen tissue and treat a type of pelvic organ prolapse called cystocele (a bladder bulge into the vagina). The trial will compare PLLA injections to a placebo in 20 women with stage 2 prolapse, monitoring safety and effectiveness over 9 months. The goal is to see if this non-surgical approach can improve symptoms and sexual function without the risks of surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Duke Urogynecology, Patterson Place

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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