PEDIATRICS

This study tests Tele-PCIT, a therapy where a coach guides parents via video call while they play with their child. It aims to improve child behavior and reduce trauma symptoms in 50 young children (ages 2-6) with disruptive behavior and a history of adverse experiences. Families…

This study looks at whether giving less intravenous (IV) fluid to critically ill children with traumatic injuries leads to fewer complications. Currently, there is no standard for how much fluid these children should receive. The trial will enroll 250 children aged 6 months to 15…

This study tests whether a high-energy diet helps infants with congenital heart disease grow and develop their brains better after heart surgery. Researchers will compare high-energy versus standard nutrition in 160 babies aged 0-6 months. The goal is to see if the special diet i…

This study tests a special dye called Cytalux that makes cancer cells glow under near-infrared light. Surgeons use it during lung surgery to find and remove hard-to-see tumors in teens (ages 6-17) with bone cancer that has spread to the lungs. The goal is to see if the dye helps …

This pilot study tests whether a topical diclofenac gel (Voltaren) works as well as oral ibuprofen for reducing pain in children aged 6-18 with ankle or knee sprains. Sixty participants will use either the gel or oral medicine three times a day for three days, then report their p…

This study tests a device called ViBandz, which uses small vibrating motors strapped to the muscles to provide targeted vibration therapy. Researchers want to see if it is easy and comfortable for children with neurological conditions to use at home. The study involves 30 childre…

This study looks at how seizures change the brain's wiring in children with drug-resistant focal epilepsy. Researchers will use special EEG recordings and MRI scans to measure brain connections. The goal is to understand if ongoing seizures cause lasting damage to brain structure…

This study follows healthy girls ages 8-14 and teens with irregular periods to learn how their menstrual cycles become regular after their first period. Researchers also include girls at risk for PCOS and compare them to women with and without PCOS. The goal is to understand norm…

This study tests whether a machine learning model can predict which children admitted to the hospital will need a medication that requires genetic testing. The goal is to offer the test earlier, so doctors can pick the safest drug or dose. The trial will involve 275 children aged…

This study compares two approaches to helping children with special health care needs transition from hospital to home. One group gets a single follow-up phone call within 72 hours, while the other gets more extended support. Researchers will track hospital readmissions, emergenc…

This study will track 10,000 children admitted to pediatric intensive care units (ICUs) across Asia. The goal is to understand what factors lead to better or worse outcomes, and to develop AI tools that can predict how long a child might need ICU care or their risk of death. No n…

This study is translating a short, 5-minute neurological test (BRIEF-HINE) into Turkish and checking if it works well for 120 high-risk infants. These babies are at risk for conditions like cerebral palsy due to premature birth or other complications. The goal is to give doctors …

This study looks at whether a new way of scoring whole-body MRI scans can reliably measure bone inflammation in children with CRMO, a rare condition causing repeated bone pain and swelling. Researchers will compare the MRI scores from different doctors and also check if changes i…

This study looks at how often children develop low blood sugar (hypoglycemia) when they fast before surgery. Fasting is required to prevent choking during anesthesia, but young children have less energy stored and may be at risk. Researchers will measure blood sugar in over 6,500…

This study tests whether a simple, step-by-step guide (called a linear cognitive aid) helps emergency medical teams treat children in life-threatening situations. About 80 EMS providers will use the guide during realistic practice scenarios. The goal is to see if the guide is eas…