PEDIATRIC CANCER

This study tests two immunotherapy drugs, durvalumab and tremelimumab, in children and teens up to age 17 with advanced solid tumors or blood cancers that have not responded to standard treatments. The first part finds the safest dose, and the second part checks if the drugs shri…

This study looks at why some children who have had cancer do not get the occupational or physical therapy they need. Researchers will interview doctors, therapists, and hospital administrators to find out what helps or hinders access. The goal is to reduce unfair differences in c…

This study creates a large registry to collect information from nearly 58,000 children diagnosed with cancer or similar conditions in the U.S. and Canada. The goal is to help researchers study patterns, causes, and characteristics of childhood cancer. Parents provide details abou…

This study tests a digital tool that lets children, teens, and young adults with cancer report their symptoms during clinic visits. Their caregivers can also report symptoms. The goal is to see if the tool is easy to use and helpful for doctors. About 83 participants will try it …

This study gathers imaging data from 367 children receiving proton therapy for cancer. Researchers will analyze daily scans to measure how much patients move during treatment and compare different imaging methods. The goal is to make radiation therapy more precise and reduce side…

This study is testing a mobile app called ATOMIC designed to help children, teens, and young adults who survived childhood cancer become more physically active. About 35 survivors aged 10 to 30 who received a specific type of chemotherapy will try the app. Researchers will see ho…

This study looks at how to best screen families of children newly diagnosed with cancer for emotional and social needs. Researchers are comparing two ways of using a questionnaire called the Psychosocial Assessment Tool (PAT) across 18 children's cancer centers in the U.S. The go…

This study looks at children who were born with a birth defect and later developed cancer. Researchers want to find out if there are shared genes that cause both conditions. They will collect DNA from up to 1,000 children and their parents to search for genetic clues. The goal is…

This study looks at how surviving a pediatric brain tumor affects children's thinking, memory, and behavior over time. Researchers will track 42 children who have finished treatment for certain brain tumors to understand these late effects. The goal is to gather information that …