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New hope for kids with tough cancers: immunotherapy combo under study

NCT ID NCT03837899

First seen Apr 22, 2026 · Last updated Apr 30, 2026 · Updated 3 times

Summary

This study is testing two immunotherapy drugs, durvalumab and tremelimumab, in children and teens up to age 17 with advanced solid tumors or certain blood cancers that have not responded to standard treatments. The first part finds the safest dose, and the second part checks if the drugs can shrink tumors. The goal is to control the disease, not cure it, as ongoing treatment may be needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Research Site

    Baltimore, Maryland, 21231, United States

  • Research Site

    Boston, Massachusetts, 02115, United States

  • Research Site

    New Hyde Park, New York, 11040, United States

  • Research Site

    Oklahoma City, Oklahoma, 73104, United States

  • Research Site

    Charleston, South Carolina, 29425, United States

  • Research Site

    Lille, 59020, France

  • Research Site

    Marseille, 13385, France

  • Research Site

    Paris, 75248, France

  • Research Site

    Cologne, 50924, Germany

  • Research Site

    Genova, 16100, Italy

  • Research Site

    Milan, 20133, Italy

  • Research Site

    Rome, 00165, Italy

  • Research Site

    Torino, 10126, Italy

  • Research Site

    Utrecht, 3584 CS, Netherlands

  • Research Site

    Barcelona, 08035, Spain

  • Research Site

    Madrid, 28009, Spain

  • Research Site

    Leeds, LS1 3EX, United Kingdom

  • Research Site

    London, WC1N 3JH, United Kingdom

  • Research Site

    Sutton, SM2 5PT, United Kingdom

Conditions

Explore the condition pages connected to this study.